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NCT05650697 · ClinicalTrials.gov registry record · Early Phase 1

Topical CBD Scar Outcomes Study

A Early Phase 1 study, sponsored by University of Oklahoma.

Not yet
Registry status
Early Phase 1
Development phase
22
Enrollment target

NCT05650697: Clinical Trial Early Phase 1 study, sponsored by University of Oklahoma.

NCT05650697 is a Early Phase 1 study that has not yet begun recruiting, run by University of Oklahoma. The registered enrollment target is 22 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05650697, a Early Phase 1 study, has not yet begun recruiting, sponsored by University of Oklahoma.

NOT YET RECRUITING
Registry status
Early Phase 1
Development phase
22 participants
Enrollment target

Study Summary

The purpose of this study is to find out what effects (good and bad) that cannabidiol (CBD) has on scar healing and appearance in patients who have undergone paramedian forehead flap reconstruction.

Primary Outcome

Proportion of patients who have a positive effect using CBD oil in combination with the silicone patch. This will be assessed using the Scar Cosmesis Assessment and Rating (SCAR) scale to determine the impact of CBD oil and silicon patch combo. This photographic evaluation of scare will be done over a period of around 7 months to evaluate the scar outcomes, using the scoring system with minimum score of 0 (being best possible outcome) and maximum score of 13 (worst possible scar outcome).

Interventions

  • BIOLOGICAL Group 1 cannabidiol (CBD) with silicone ointment
  • BIOLOGICAL Group 2 silicone patch

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2026-09
Est. Completion 2027-12
Phase Early Phase 1
University of Oklahoma

358 total trials

What is known before NCT05650697 opens enrollment

NCT05650697 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (58% lower).

The record links to 0 conditions, and to 2 interventions - of which Group 1 cannabidiol (CBD) with silicone ointment is the first listed.

NCT05650697 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05650697 about?

NCT05650697 is a clinical study titled "Topical CBD Scar Outcomes Study". The purpose of this study is to find out what effects (good and bad) that cannabidiol (CBD) has on scar healing and appearance in patients who have undergone paramedian forehead flap reconstruction.

What is the current status of trial NCT05650697?

This trial is currently not yet recruiting. It is a Early Phase 1 study. The enrollment target is 22 participants. The study started on 2026-09. Estimated completion is 2027-12.

What interventions are being tested in trial NCT05650697?

The interventions under investigation include: Group 1 cannabidiol (CBD) with silicone ointment (BIOLOGICAL), Group 2 silicone patch (BIOLOGICAL).

Who is sponsoring clinical trial NCT05650697?

This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05650697's enrollment target sits among peer trials

22 1104th of 2000 higher than 871 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05650697, the US trial registry maintained by the National Library of Medicine. NCT05650697 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.