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TrEatment Approach in the Multimodal Era Registry
NCT05629052 · View on ClinicalTrials.gov ↗
Study Summary
The goal of this observational patient registry is to learn how expert centers treat patients with chronic thromboembolic pulmonary hypertension (CTEPH). CTEPH is a condition in which blood clots block the blood vessels in the lungs. There are currently three treatment options for patients with CTEPH: * surgery to remove blood clots from large vessels in the lungs (pulmonary endarterectomy (PEA)) * the use of a small balloon to unblock smaller blood vessels (balloon pulmonary angioplasty (BPA)) * drugs Patients can also receive a combination of these treatments. The main question this registry aims to answer are: * How many patients receive a given kind of treatment? * How do expert centers combine the different treatments? * Are patients doing better after they receive a given kind of treatment? * How many patients are alive 1, 3 and 5 years after they receive a given kind of treatment? Participants will receive the same treatments that they would receive if they did not participate in the study. During the study, patients will visit their doctors as they would do normally. The doctors will collect information on the patients' health and enter it into the study database. The follow-up time will be at least 3 years for all patients.
Conditions Studied
Interventions
- PROCEDURE Pulmonary endarterectomy
- PROCEDURE Balloon pulmonary angioplasty
- DRUG Pulmonary hypertension (PH)-specific medication
Study Locations (20)
Other
- Hospital Universitario Fundación Favaloro — Buenos Aires
- University Hospital Vienna — Vienna
- University Hospitals Leuven — Leuven
- Santa Casa — Porto Alegre
- China-Japan Friendship Hospital — Beijing
- Shaio Clinic Foundation — Bogotá
- General University Hospital — Prague
- Aarhus University Hospital — Aarhus
- Kerckhoff Clinic, Department of Thoracic Surgery — Bad Nauheim
- Narayana Institute of Cardiac Science — Bangalore
- University of Bologna — Bologna
- Okayama Medical Center — Okayama
- National Cerebral and Cardiovascular Center — Osaka
- National Heart Institute — Mexico City
- Department of Cardiac and Vascular Diseases, John Paul II Hospital — Krakow
California
- University of California San Diego — San Diego
Illinois
- Northwestern University — Evanston
North Carolina
- Duke University — Durham
Texas
- UT Southwestern — Dallas
Ontario
- Toronto General Hospital — Toronto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2023-04-12 |
| Est. Completion | 2028-04 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05629052
The ClinicalTrials.gov registry entry for NCT05629052 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is International CTEPH Association, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Chronic Thromboembolic Pulmonary Hypertension appearing as the primary indexed condition, and to 3 interventions — of which Pulmonary endarterectomy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05629052 reports 20 study locations spanning 6 distinct geographic areas — top geographies include Other, California, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05629052 about?
NCT05629052 is a clinical study titled "TrEatment Approach in the Multimodal Era Registry". The goal of this observational patient registry is to learn how expert centers treat patients with chronic thromboembolic pulmonary hypertension (CTEPH). CTEPH is a condition in which blood clots block the blood vessels in the lungs. There are currently three treatment options for patients with CTEP...
What is the current status of trial NCT05629052?
This trial is currently active not recruiting. The enrollment target is 1,000 participants. The study started on 2023-04-12. Estimated completion is 2028-04.
What conditions does trial NCT05629052 study?
This clinical trial studies the following conditions: Chronic Thromboembolic Pulmonary Hypertension, CTEPH. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05629052?
The interventions under investigation include: Pulmonary endarterectomy (PROCEDURE), Balloon pulmonary angioplasty (PROCEDURE), Pulmonary hypertension (PH)-specific medication (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05629052?
This trial is sponsored by International CTEPH Association, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05629052 being conducted?
This trial has 20 study locations across California, Illinois, North Carolina, Texas, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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