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NCT05616689 · ClinicalTrials.gov registry record · NA
Bundled Hyperpolypharmacy Deprescribing
A NA study of Polypharmacy, sponsored by Kaiser Permanente.
- Completed
- Registry status
- NA
- Development phase
- 2,471
- Enrollment target
- 1
- Study location
NCT05616689 is a NA study of Polypharmacy that has completed, run by Kaiser Permanente. The registered enrollment target is 2,471 participants, above the 1,292-participant average among 8 other Polypharmacy trials with a reported enrollment target (91% higher). The trial reports 1 study location across 1 state.
The verdict
NCT05616689, a NA study of Polypharmacy, has completed, sponsored by Kaiser Permanente.
- COMPLETED
- Registry status
- NA
- Development phase
- 2,471 participants
- Enrollment target
- 1
- Study location
Study Summary
Older patients using many prescription drugs (hyperpolypharmacy) may be at increased risk of adverse drug effects. This randomized controlled trial tested the effectiveness and safety of a quality intervention intended to reduce hyperpolypharmacy. The study was set at Kaiser Permanente Northern California, an integrated health system with multiple pre-existing deprescribing workflows. Eligible patients were aged ≥76 years using ≥10 prescription medications. The intervention included physician-pharmacist collaborative drug therapy management, standard-of-care practice recommendations, shared decision-making, and deprescribing protocols administered by telephone over multiple cycles for a maximum of 180 days after allocation. A priori primary effectiveness endpoints included change in the number of medications and in the prevalence of geriatric syndrome from 181-365 days after allocation. Second endpoints included utilization and adverse drug withdrawal effects. Information was obtained from the electronic health record.
Conditions Studied
Interventions
- OTHER Bundled hyperpolypharmacy
Study Locations (1)
California
- Kaiser Permanente Division of Research - Oakland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,471 participants |
| Start Date | 2020-10-19 |
| Est. Completion | 2023-05-24 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05616689
The ClinicalTrials.gov registry entry for NCT05616689 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 2,471 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 1,292-participant average among 8 other Polypharmacy trials with a reported enrollment target (91% higher). The listed sponsor is Kaiser Permanente, which has 294 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Polypharmacy appearing as the primary indexed condition, and to 1 intervention - of which Bundled hyperpolypharmacy is the first listed.
NCT05616689 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05616689 about?
NCT05616689 is a clinical study titled "Bundled Hyperpolypharmacy Deprescribing". Older patients using many prescription drugs (hyperpolypharmacy) may be at increased risk of adverse drug effects. This randomized controlled trial tested the effectiveness and safety of a quality intervention intended to reduce hyperpolypharmacy. The study was set at Kaiser Permanente Northern Cali...
What is the current status of trial NCT05616689?
This trial is currently completed. It is a NA study. The enrollment target is 2,471 participants. The study started on 2020-10-19. Estimated completion is 2023-05-24.
What conditions does trial NCT05616689 study?
This clinical trial studies the following conditions: Polypharmacy.
What interventions are being tested in trial NCT05616689?
The interventions under investigation include: Bundled hyperpolypharmacy (OTHER).
Who is sponsoring clinical trial NCT05616689?
This trial is sponsored by Kaiser Permanente, which has 294 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05616689 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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