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ACTIVE NOT RECRUITING Phase 1

Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG

NCT05610891 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this dose finding study is to evaluate the safety and efficacy of 2 different dose levels of CLR 131 in children, adolescents and young adults with relapsed or refractory high-grade glioma (HGG).

Conditions Studied

Interventions

  • DRUG CLR 131

Study Locations (8)

Texas

  • UT Southwestern Medical Center — Dallas
  • Texas Children's Cancer Center, Baylor College of Medicine — Houston

California

  • Stanford University — Palo Alto

New York

  • Memorial Sloan Kettering Cancer Center — New York

Ohio

  • Cincinnati Children's Hospital Medical Center — Cincinnati

Pennsylvania

  • Children's Hospital of Philadelphia — Philadelphia

Wisconsin

  • University of Wisconsin, Carbone Cancer Center — Madison

Ontario

  • Hospital for Sick Children — Toronto

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2023-10-01
Est. Completion 2026-09
Phase Phase 1

Sponsor

Cellectar Biosciences

6 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05610891

The ClinicalTrials.gov registry entry for NCT05610891 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Cellectar Biosciences, which has 6 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with High-Grade Glioma appearing as the primary indexed condition, and to 1 intervention — of which CLR 131 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05610891 reports 8 study locations spanning 7 distinct geographic areas — top geographies include Texas, California, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05610891 about?

NCT05610891 is a clinical study titled "Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG". The purpose of this dose finding study is to evaluate the safety and efficacy of 2 different dose levels of CLR 131 in children, adolescents and young adults with relapsed or refractory high-grade glioma (HGG).

What is the current status of trial NCT05610891?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2023-10-01. Estimated completion is 2026-09.

What conditions does trial NCT05610891 study?

This clinical trial studies the following conditions: High-Grade Glioma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05610891?

The interventions under investigation include: CLR 131 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05610891?

This trial is sponsored by Cellectar Biosciences, which has 6 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05610891 being conducted?

This trial has 8 study locations across California, New York, Ohio, Pennsylvania, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial