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NCT05464940 · ClinicalTrials.gov registry record · NA
Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction
A NA study, sponsored by Kansas City Heart Rhythm Research Foundation.
- Not yet
- Registry status
- NA
- Development phase
- 100
- Enrollment target
NCT05464940: Clinical Trial NA study, sponsored by Kansas City Heart Rhythm Research Foundation.
NCT05464940 is a NA study that has not yet begun recruiting, run by Kansas City Heart Rhythm Research Foundation. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05464940, a NA study, has not yet begun recruiting, sponsored by Kansas City Heart Rhythm Research Foundation.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
Study Summary
This "How caffeine Induces Atrial Tachyarrhythmias" trial will be a multi-center, randomized, double-blinded trial of intravenous caffeine versus placebo among patients undergoing pulmonary vein isolation procedures for Atrial Fibrillation(AF).
Primary Outcome
Induction of Atrial fibrillation will be attempted by pacing and isoproterenol infusion following study drug infusion. The ability to induce atrial fibrillation (yes or no) will be recorded as the primary outcome.
Interventions
- OTHER Intravenous caffeine
- OTHER Masked Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-09 |
| Est. Completion | 2026-06 |
| Phase | NA |
What is known before NCT05464940 opens enrollment
NCT05464940 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 2 interventions - of which Intravenous caffeine is the first listed.
NCT05464940 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05464940 about?
NCT05464940 is a clinical study titled "Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction". This "How caffeine Induces Atrial Tachyarrhythmias" trial will be a multi-center, randomized, double-blinded trial of intravenous caffeine versus placebo among patients undergoing pulmonary vein isolation procedures for Atrial Fibrillation(AF).
What is the current status of trial NCT05464940?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2025-09. Estimated completion is 2026-06.
What interventions are being tested in trial NCT05464940?
The interventions under investigation include: Intravenous caffeine (OTHER), Masked Placebo (OTHER).
Who is sponsoring clinical trial NCT05464940?
This trial is sponsored by Kansas City Heart Rhythm Research Foundation, which has 22 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05464940's enrollment target sits among peer trials
100 840th of 2000 higher than 1,081 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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