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NCT05464511 · ClinicalTrials.gov registry record · NA
Impact of Steerable Delivery Sheaths on Successful Closure of LA A With AMULET
A NA study, sponsored by Kansas City Heart Rhythm Research Foundation.
- Not yet
- Registry status
- NA
- Development phase
- 300
- Enrollment target
NCT05464511: Clinical Trial NA study, sponsored by Kansas City Heart Rhythm Research Foundation.
NCT05464511 is a NA study that has not yet begun recruiting, run by Kansas City Heart Rhythm Research Foundation. The registered enrollment target is 300 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (79% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05464511, a NA study, has not yet begun recruiting, sponsored by Kansas City Heart Rhythm Research Foundation.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 300 participants
- Enrollment target
Study Summary
The novel Amplatzer steerable delivery sheath (Abbott Vascular) is found to be safe and effective in performing LAAO procedure. However, the procedural outcomes have not been compared with the traditional non-steerable fixed curve sheath. In this study investigators aim to compare the outcome of patients undergoing left atrial appendage occlusion with the dual mechanism closure Amulet device using non-steerable fixed curve sheath versus a novel steerable sheath.
Primary Outcome
Acute closure ( less than or equal to 3mm) of the left atrial appendage after Left Atrial Appedage Occlusion(LAAO) procedure
Interventions
- OTHER Left atrial appendage occlusion with the dual mechanism closure Amulet device using a novel steerable sheath.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2026-01 |
| Est. Completion | 2026-12 |
| Phase | NA |
What is known before NCT05464511 opens enrollment
NCT05464511 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (79% lower).
The record links to 0 conditions, and to 1 intervention - of which Left atrial appendage occlusion with the dual mechanism closure Amulet device using a novel steerable sheath. is the first listed.
NCT05464511 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05464511 about?
NCT05464511 is a clinical study titled "Impact of Steerable Delivery Sheaths on Successful Closure of LA A With AMULET". The novel Amplatzer steerable delivery sheath (Abbott Vascular) is found to be safe and effective in performing LAAO procedure. However, the procedural outcomes have not been compared with the traditional non-steerable fixed curve sheath. In this study investigators aim to compare the outcome of pat...
What is the current status of trial NCT05464511?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 300 participants. The study started on 2026-01. Estimated completion is 2026-12.
What interventions are being tested in trial NCT05464511?
The interventions under investigation include: Left atrial appendage occlusion with the dual mechanism closure Amulet device using a novel steerable sheath. (OTHER).
Who is sponsoring clinical trial NCT05464511?
This trial is sponsored by Kansas City Heart Rhythm Research Foundation, which has 22 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05464511's enrollment target sits among peer trials
300 330th of 2000 higher than 1,630 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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