Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05428072 · ClinicalTrials.gov registry record · Early Phase 1
Alcohol, Gut Leakiness, & Liver Disease
A Early Phase 1 study, sponsored by Rush University Medical Center.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 195
- Enrollment target
NCT05428072 is a Early Phase 1 study that has completed, run by Rush University Medical Center. The registered enrollment target is 195 participants.
The verdict
NCT05428072, a Early Phase 1 study, has completed, sponsored by Rush University Medical Center.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 195 participants
- Enrollment target
Study Summary
The goal of this study is to investigate the role of gut leakiness in alcoholic liver disease. Gut leakiness may be the missing susceptibility factor that explains why some alcoholics develop liver disease and others don't. For this study, subjects 480 (240 male, 240 female, ages 18-80) will be recruited. Alcoholic subjects will be recruited from outpatient \& inpatient alcohol detoxification units from Rush, Loyola \& two halfway houses (one for women, one for men); patients with liver disease from GI/Hepatology Services at Rush, Hines VA Hosp \& Loyola University; and controls from hospital staffs. All subjects will fill out a detailed questionnaire, be interviewed by the study coordinator \& undergo an exam by the PI to ensure that all inclusion criteria are satisfied. All subjects will have a urine collection for tests of intestinal permeability (urinary sugars). Gut leakiness will be determined by the amount of sugars in the urine.
Interventions
- DRUG Aspirin Challenge
- OTHER Sugar test
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 195 participants |
| Start Date | 2003-01 |
| Est. Completion | 2015-03 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05428072
The ClinicalTrials.gov registry entry for NCT05428072 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 195 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rush University Medical Center, which has 320 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Aspirin Challenge is the first listed.
NCT05428072 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05428072 about?
NCT05428072 is a clinical study titled "Alcohol, Gut Leakiness, & Liver Disease". The goal of this study is to investigate the role of gut leakiness in alcoholic liver disease. Gut leakiness may be the missing susceptibility factor that explains why some alcoholics develop liver disease and others don't. For this study, subjects 480 (240 male, 240 female, ages 18-80) will be recr...
What is the current status of trial NCT05428072?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 195 participants. The study started on 2003-01. Estimated completion is 2015-03.
What interventions are being tested in trial NCT05428072?
The interventions under investigation include: Aspirin Challenge (DRUG), Sugar test (OTHER).
Who is sponsoring clinical trial NCT05428072?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.