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NCT05380362 · ClinicalTrials.gov registry record · NA

Prospective Randomized Endovascular Therapy in Multiple Sclerosis

A NA study, sponsored by University at Buffalo.

Completed
Registry status
NA
Development phase
30
Enrollment target

NCT05380362 is a NA study that has completed, run by University at Buffalo. The registered enrollment target is 30 participants.

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The verdict

NCT05380362, a NA study, has completed, sponsored by University at Buffalo.

COMPLETED
Registry status
NA
Development phase
30 participants
Enrollment target

Study Summary

1. To assess the safety of endovascular therapy (balloon angioplasty) for venous stenoses in MS patients with CCSVI as documented by sonographic (extracranial echocolor-Doppler (ECD) and transcranial color Doppler (TCD) 2. To study the morphology of the venous anomalies by using intraluminal ultrasound (IVUS). 3. To evaluate preliminary efficacy of endovascular therapy (angioplasty) as measured by clinical (relapse rate, disability progression (EDSS)), sonographic (ECD/TCD) and MRI/MRV parameters. 4. To evaluate change in patients self-reported QOL following the therapeutic angioplasty 5. To evaluate whether changes in QOL, fatigue, MSFC or attention following therapeutic angioplasty are associated with brain changes as measured by functional MRI (fMRI).

Interventions

  • OTHER Venous Angioplasty
  • OTHER Sham Angioplasty

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2010-06
Est. Completion 2013-04
Phase NA

Sponsor

University at Buffalo

67 total trials

What the Registry Record Tells You About NCT05380362

The ClinicalTrials.gov registry entry for NCT05380362 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University at Buffalo, which has 67 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Venous Angioplasty is the first listed.

NCT05380362 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05380362 about?

NCT05380362 is a clinical study titled "Prospective Randomized Endovascular Therapy in Multiple Sclerosis". 1. To assess the safety of endovascular therapy (balloon angioplasty) for venous stenoses in MS patients with CCSVI as documented by sonographic (extracranial echocolor-Doppler (ECD) and transcranial color Doppler (TCD) 2. To study the morphology of the venous anomalies by using intraluminal ultraso...

What is the current status of trial NCT05380362?

This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2010-06. Estimated completion is 2013-04.

What interventions are being tested in trial NCT05380362?

The interventions under investigation include: Venous Angioplasty (OTHER), Sham Angioplasty (OTHER).

Who is sponsoring clinical trial NCT05380362?

This trial is sponsored by University at Buffalo, which has 67 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.