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RECRUITING NA

Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

NCT05376267 · View on ClinicalTrials.gov ↗

Study Summary

This is a multicenter trial to establish the efficacy of cooling and the optimal duration of induced hypothermia for neuroprotection in pediatric comatose survivors of cardiac arrest. The study team hypothesizes that longer durations of cooling may improve either the proportion of children that attain a good neurobehavioral recovery or may result in better recovery among the proportion already categorized as having a good outcome.

Interventions

  • DEVICE Therapeutic Hypothermia

Study Locations (20)

California

  • Memorial Health - Miller Children's and Women's Hospital of Long Beach — Long Beach
  • Children's Hospital of Los Angeles — Los Angeles
  • University of California Los Angeles (UCLA) Mattel Children's Hospital — Los Angeles
  • University of California - Oakland / UCSF Benoiff Children's Hospital Oakland — Oakland
  • Children's Hospital of Orange County — Orange
  • University of California, Davis — Sacramento
  • University of California - San Francisco (UCSF) Benioff Children's Hospital San Francisco — San Francisco
  • Stanford — Santa Clara

Illinois

  • Ann & Robert Lurie Children's Hospital of Chicago — Chicago
  • Comer Children's Hospital, University of Chicago — Chicago
  • Children's Hospital of Illinois — Peoria

Arizona

  • Phoenix Children's Hospital — Phoenix
  • Banner University Medical Center - Tucson — Tucson

Florida

  • University of Florida (UF) Health Shands Children's Hospital — Gainesville
  • University of Miami — Miami

Maryland

  • University of Maryland Children's Hospital — Baltimore
  • Johns Hopkins Medicine Children's Center — Baltimore

Alabama

  • University of Alabama at Birmingham / Children's of Alabama — Birmingham

Indiana

  • Riley Children's Health — Indianapolis

Iowa

  • University of Iowa, Carver College of Medicine — Iowa City

Trial Details

FieldValue
Enrollment Target 900 participants
Start Date 2022-08-05
Est. Completion 2028-03-31
Phase NA

Sponsor

University of Michigan

1,126 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05376267

The ClinicalTrials.gov registry entry for NCT05376267 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 900 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Michigan, which has 1,126 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Cardiac Arrest, Out-Of-Hospital appearing as the primary indexed condition, and to 1 intervention — of which Therapeutic Hypothermia is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05376267 reports 20 study locations spanning 8 distinct geographic areas — top geographies include California, Illinois, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05376267 about?

NCT05376267 is a clinical study titled "Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)". This is a multicenter trial to establish the efficacy of cooling and the optimal duration of induced hypothermia for neuroprotection in pediatric comatose survivors of cardiac arrest. The study team hypothesizes that longer durations of cooling may improve either the proportion of children that att...

What is the current status of trial NCT05376267?

This trial is currently recruiting. It is a NA study. The enrollment target is 900 participants. The study started on 2022-08-05. Estimated completion is 2028-03-31.

What conditions does trial NCT05376267 study?

This clinical trial studies the following conditions: Cardiac Arrest, Out-Of-Hospital, Hypoxia-Ischemia, Brain, Hypothermia, Induced. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05376267?

The interventions under investigation include: Therapeutic Hypothermia (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05376267?

This trial is sponsored by University of Michigan, which has 1,126 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05376267 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial