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NCT05350579 · ClinicalTrials.gov registry record · NA
Yogurt Supplementation to Alter Bone Biomarkers, the Gut Microbiota and Inflammation in Older Adults
A NA study, sponsored by University of Massachusetts, Lowell.
- Terminated
- Registry status
- NA
- Development phase
- 33
- Enrollment target
NCT05350579: Clinical Trial NA study, sponsored by University of Massachusetts, Lowell.
NCT05350579 is a NA study that was terminated before completion, run by University of Massachusetts, Lowell. The registered enrollment target is 33 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05350579, a NA study, was terminated before completion, sponsored by University of Massachusetts, Lowell.
- TERMINATED
- Registry status
- NA
- Development phase
- 33 participants
- Enrollment target
Study Summary
Caribbean Latino adults are a vulnerable population at risk for developing osteoporosis. In addition to lifestyle factors, such as dietary intake, the investigators hypothesize that a unhealthy gut microbial environment coupled with high inflammation contributes to the risk of developing osteoporosis. There has been little research conducted on mechanisms underpinning how a low-intensity dietary intervention, including supplementation with daily yogurt, can affect the gut health of Caribbean Latino adults. The study objectives are to: 1) determine whether daily yogurt supplementation reduces bone turnover (biomarkers of overall bone health) and inflammation compared to a control group that maintains their usual diet (void of yogurt); and 2) collect preliminary data on the effects of daily yogurt supplementation on the gut microbiome compared to diet control group.
Primary Outcome
To evaluate bone health at baseline and at study completion, bone formation markers, pro-collagen I alpha 1 (P1NP) pg/mL and osteocalcin (OC) pg/mL will be measured in serum using ELISA kits.
Interventions
- OTHER Yogurt Intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2019-03-28 |
| Est. Completion | 2020-03-25 |
| Phase | NA |
Why NCT05350579 stopped before completion
NCT05350579 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Yogurt Intervention is the first listed.
NCT05350579 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05350579 about?
NCT05350579 is a clinical study titled "Yogurt Supplementation to Alter Bone Biomarkers, the Gut Microbiota and Inflammation in Older Adults". Caribbean Latino adults are a vulnerable population at risk for developing osteoporosis. In addition to lifestyle factors, such as dietary intake, the investigators hypothesize that a unhealthy gut microbial environment coupled with high inflammation contributes to the risk of developing osteoporosi...
What is the current status of trial NCT05350579?
This trial is currently terminated. It is a NA study. The enrollment target is 33 participants. The study started on 2019-03-28. Estimated completion is 2020-03-25.
What interventions are being tested in trial NCT05350579?
The interventions under investigation include: Yogurt Intervention (OTHER).
Who is sponsoring clinical trial NCT05350579?
This trial is sponsored by University of Massachusetts, Lowell, which has 9 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05350579's enrollment target sits among peer trials
33 1574th of 2000 higher than 423 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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