Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05338333 · ClinicalTrials.gov registry record · NA
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
A NA study of Presbyopia, sponsored by Alcon Research.
- Completed
- Registry status
- NA
- Development phase
- 101
- Enrollment target
- 8
- Study locations
NCT05338333: Completed NA study of Presbyopia, sponsored by Alcon Research.
NCT05338333 is a NA study of Presbyopia that has completed, run by Alcon Research. The registered enrollment target is 101 participants, below the 268-participant average among 38 other Presbyopia trials with a reported enrollment target (62% lower). The trial reports 8 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05338333, a NA study of Presbyopia, has completed, sponsored by Alcon Research.
- COMPLETED
- Registry status
- NA
- Development phase
- 101 participants
- Enrollment target
- 8
- Study locations
Study Summary
The primary objective of this study is to demonstrate noninferiority in visual acuity at distance when wearing the test contact lenses (LID210464) compared to the control contact lenses (AOHG MF) after 30 days of wear.
Primary Outcome
Visual acuity (VA) was assessed with study lenses in place under high contrast, high illumination. VA was collected for both eyes together using logarithmic of the Minimum Angle of Resolution (logMAR) charts. A logMAR acuity of 0.0 corresponds to 20/20 Snellen acuity (normal visual acuity), with a negative value denoting better than 20/20 visual acuity.
Conditions Studied
Interventions
- DEVICE Lehfilcon A multifocal contact lenses
- DEVICE Lotrafilcon B multifocal contact lenses
- DEVICE CLEAR CARE®
Study Locations (8)
Florida
- Kindred Optics at Maitland Vision - Maitland
- Vision Health Institute - Orlando
Minnesota
- The Eye Doctors, Inc. - Eden Prairie
- Complete Eye Care of Medina - Medina
Kansas
- Kannarr Eye Care LLC - Pittsburg
Ohio
- ProCare Vision Centers, Inc. - Granville
Rhode Island
- West Bay Eye Associates - Warwick
Tennessee
- Optometry Group, PLLC - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 101 participants |
| Start Date | 2022-05-27 |
| Est. Completion | 2022-09-01 |
| Phase | NA |
What the finished NCT05338333 record still lists
NCT05338333 is an interventional study that assigns participants to a tested intervention. The registered 101 participants enrollment target is mid-sized for trials with a published cap, below the 268-participant average among 38 other Presbyopia trials with a reported enrollment target (62% lower).
The record links to 1 condition, with Presbyopia appearing as the primary indexed condition, and to 3 interventions - of which Lehfilcon A multifocal contact lenses is the first listed.
NCT05338333 lists 8 locations in 6 states (Florida, Minnesota, Kansas).
Frequently Asked Questions
What is clinical trial NCT05338333 about?
NCT05338333 is a clinical study titled "Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses". The primary objective of this study is to demonstrate noninferiority in visual acuity at distance when wearing the test contact lenses (LID210464) compared to the control contact lenses (AOHG MF) after 30 days of wear.
What is the current status of trial NCT05338333?
This trial is currently completed. It is a NA study. The enrollment target is 101 participants. The study started on 2022-05-27. Estimated completion is 2022-09-01.
What conditions does trial NCT05338333 study?
This clinical trial studies the following conditions: Presbyopia.
What interventions are being tested in trial NCT05338333?
The interventions under investigation include: Lehfilcon A multifocal contact lenses (DEVICE), Lotrafilcon B multifocal contact lenses (DEVICE), CLEAR CARE® (DEVICE).
Who is sponsoring clinical trial NCT05338333?
This trial is sponsored by Alcon Research, which has 275 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05338333 being conducted?
This trial has 8 study locations across Florida, Kansas, Minnesota, Ohio, Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Presbyopia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05338333's enrollment target sits among peer trials
101 15th of 38 higher than 24 of 38 other Presbyopia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Presbyopia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Post Market Clinical Evaluation of Clareon PanOptix Pro and Clareon PanOptix Pro Toric IOLs
RECRUITING · NA
-
A Clinical Comparison of Proclear® 1 Day Multifocal and Clariti® 1 Day Multifocal 3 Add
RECRUITING · NA
-
Presbyopic Wear Experience With Multifocal Lenses Compared to Single Vision Lenses and Reading Glasses
RECRUITING · NA
-
Clinical Applications of Advanced Ophthalmic Imaging
RECRUITING · NA
-
Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix
ACTIVE NOT RECRUITING · NA
-
Clinical Evaluation of a Small Aperture Extended Depth of Focus Intraocular Lens
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04033497 · 101 participants · NA
Treatment Response Assessment Maps to Delineate Necrosis From Tumor After Stereotactic Radiation in Brain Metastases
- NCT05111574 · 101 participants · Phase 2
Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery
- NCT05984680 · 101 participants
COPD Care Pathway Among Patients With Cancer
- NCT06266299 · 101 participants · Phase 1
A Study of KK2269 in Adult Participants With Solid Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI