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NCT05182489 · ClinicalTrials.gov registry record · NA
Adaptix RCT Evaluating Adaptix™ Versus PEEK Cages
A NA study of Degenerative Disc Disease and Spondylolisthesis, sponsored by Ohio State University.
- Active
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT05182489: Active NA study of Degenerative Disc Disease and Spondylolisthesis, sponsored by Ohio State University.
NCT05182489 is a NA study of Degenerative Disc Disease and Spondylolisthesis that is active but no longer recruiting, run by Ohio State University. The registered enrollment target is 100 participants, below the 166-participant average among 42 other Degenerative Disc Disease trials with a reported enrollment target (40% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05182489, a NA study of Degenerative Disc Disease and Spondylolisthesis, is active but no longer recruiting, sponsored by Ohio State University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this randomized controlled trial is to assess and compare radiographic and clinical outcomes in patients who are to undergo combined interbody/posterolateral lumbar fusion procedures, supplemented with pedicle screw instrumentation, using one of the following interbody cages; the Medtronic Adaptix™ cage with roughened micro and nano-textured titanium surfaces or the CAPSTONE® poly-ether-ether-ketone cage.
Primary Outcome
A subject will be considered a success if fusion is a Grade BSF-3 at 6 months. The primary outcome measure of effectiveness will be determined by the fusion rate at 6 months post-operatively in subjects implanted with either titanium cage as compared to the PEEK cage.
Conditions Studied
Interventions
- DEVICE Medtronic Adaptix™ titanium implants
- DEVICE Medtronic CAPSTONE® PEEK cage
Study Locations (1)
Ohio
- The Ohio State University Wexner Medical Center Neurological Surgery - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2021-11-19 |
| Est. Completion | 2026-04-01 |
| Phase | NA |
What the registry record for NCT05182489 still lists
NCT05182489 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 166-participant average among 42 other Degenerative Disc Disease trials with a reported enrollment target (40% lower).
The record links to 5 conditions, with Degenerative Disc Disease appearing as the primary indexed condition, and to 2 interventions - of which Medtronic Adaptix™ titanium implants is the first listed.
NCT05182489 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT05182489 about?
NCT05182489 is a clinical study titled "Adaptix RCT Evaluating Adaptix™ Versus PEEK Cages". The purpose of this randomized controlled trial is to assess and compare radiographic and clinical outcomes in patients who are to undergo combined interbody/posterolateral lumbar fusion procedures, supplemented with pedicle screw instrumentation, using one of the following interbody cages; the Medt...
What is the current status of trial NCT05182489?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2021-11-19. Estimated completion is 2026-04-01.
What conditions does trial NCT05182489 study?
This clinical trial studies the following conditions: Degenerative Disc Disease, Spondylolisthesis, Spinal Canal Stenosis, Osteophyte, Bony Growth Formation.
What interventions are being tested in trial NCT05182489?
The interventions under investigation include: Medtronic Adaptix™ titanium implants (DEVICE), Medtronic CAPSTONE® PEEK cage (DEVICE).
Who is sponsoring clinical trial NCT05182489?
This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05182489 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Degenerative Disc Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05182489's enrollment target sits among peer trials
100 20th of 42 higher than 21 of 42 other Degenerative Disc Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Degenerative Disc Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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