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NCT05119036 · ClinicalTrials.gov registry record · NA
Adjuvant Treatment Deintensification After Transoral Surgery for Human Papillomavirus-Positive Squamous Cell Carcinoma
A NA study of HPV Positive Oropharyngeal Squamous Cell Carcinoma and Squamous Cell Carcinoma of the Oropharynx, sponsored by Indiana University.
- Active
- Registry status
- NA
- Development phase
- 83
- Enrollment target
- 2
- Study locations
NCT05119036 is a NA study of HPV Positive Oropharyngeal Squamous Cell Carcinoma and Squamous Cell Carcinoma of the Oropharynx that is active but no longer recruiting, run by Indiana University. The registered enrollment target is 83 participants, roughly in line with the 87-participant average among 16 other HPV Positive Oropharyngeal Squamous Cell Carcinoma trials with a reported enrollment target. The trial reports 2 study locations across 1 state.
The verdict
NCT05119036, a NA study of HPV Positive Oropharyngeal Squamous Cell Carcinoma and Squamous Cell Carcinoma of the Oropharynx, is active but no longer recruiting, sponsored by Indiana University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 83 participants
- Enrollment target
- 2
- Study locations
Study Summary
Oropharyngeal squamous cell carcinoma (OPSCC), commonly known as throat cancer or tonsil cancer, has seen a dramatic rise in incidence over the last twenty years. There are two types of OPSCC: human papillomavirus-positive (HPV+) and human papillomavirus-negative (HPV-). People with OPSCC, regardless of their type, typically receive standard treatment with a combination of chemotherapy, radiation therapy, and surgery. Due to the intensity of standard treatment, survivors may experience unwanted long-term side effects. The goal of this research study is to see if intensifying (stopping or scaling back) treatment still provides the same, or perhaps even better, results when compared to standard treatment.
Conditions Studied
Interventions
- RADIATION 44 doses of radiation
- RADIATION 54 doses of radiation
Study Locations (2)
Indiana
- IU Health Joe and Shelly Schwarz Cancer Center - Carmel
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 83 participants |
| Start Date | 2022-05-12 |
| Est. Completion | 2026-04 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05119036
The ClinicalTrials.gov registry entry for NCT05119036 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 83 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 87-participant average among 16 other HPV Positive Oropharyngeal Squamous Cell Carcinoma trials with a reported enrollment target. The listed sponsor is Indiana University, which has 890 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with HPV Positive Oropharyngeal Squamous Cell Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which 44 doses of radiation is the first listed.
NCT05119036 reports 2 study locations spanning 1 distinct geographic area - top geographies include Indiana.
Frequently Asked Questions
What is clinical trial NCT05119036 about?
NCT05119036 is a clinical study titled "Adjuvant Treatment Deintensification After Transoral Surgery for Human Papillomavirus-Positive Squamous Cell Carcinoma". Oropharyngeal squamous cell carcinoma (OPSCC), commonly known as throat cancer or tonsil cancer, has seen a dramatic rise in incidence over the last twenty years. There are two types of OPSCC: human papillomavirus-positive (HPV+) and human papillomavirus-negative (HPV-). People with OPSCC, regardles...
What is the current status of trial NCT05119036?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 83 participants. The study started on 2022-05-12. Estimated completion is 2026-04.
What conditions does trial NCT05119036 study?
This clinical trial studies the following conditions: HPV Positive Oropharyngeal Squamous Cell Carcinoma, Squamous Cell Carcinoma of the Oropharynx.
What interventions are being tested in trial NCT05119036?
The interventions under investigation include: 44 doses of radiation (RADIATION), 54 doses of radiation (RADIATION).
Who is sponsoring clinical trial NCT05119036?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05119036 being conducted?
This trial has 2 study locations across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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