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NCT05101187 · ClinicalTrials.gov registry record · Phase 3

Olorofim Aspergillus Infection Study

A Phase 3 study of Invasive Aspergillosis, sponsored by F2G Biotech.

Active
Registry status
Phase 3
Development phase
225
Enrollment target
20
Study locations

NCT05101187 is a Phase 3 study of Invasive Aspergillosis that is active but no longer recruiting, run by F2G Biotech. The registered enrollment target is 225 participants. The trial reports 20 study locations across 15 states.

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The verdict

NCT05101187, a Phase 3 study of Invasive Aspergillosis, is active but no longer recruiting, sponsored by F2G Biotech.

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
225 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to compare treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with IFD caused by proven IA or probable lower respiratory tract disease Aspergillus species (invasive aspergillosis, IA).

Conditions Studied

Interventions

  • DRUG Olorofim
  • DRUG AmBisome®

Study Locations (20)

California

  • City of Hope National Medical Center - Duarte
  • University of California Davis Health System - Sacramento
  • UCSF Helen Diller Medical Center at Parnassus Heights - San Francisco

Maryland

  • The Johns Hopkins Hospital - Baltimore
  • NIH Clinical Center ,NIAID,NIH - Bethesda

Minnesota

  • University of Minnesota - Minneapolis
  • Mayo Clinic - Rochester - Rochester

North Carolina

  • University of North Carolina at Chapel Hill - Chapel Hill
  • Duke Department of Medicine Infectious Diseases Division - Durham

Alabama

  • University of Alabama at Birmingham - Birmingham

Florida

  • University of Florida - Gainesville

Georgia

  • Augusta University - Augusta

Illinois

  • University of Chicago Medical Center - Chicago

Trial Details

FieldValue
Enrollment Target 225 participants
Start Date 2022-03-31
Est. Completion 2026-11-01
Phase Phase 3

Sponsor

F2G Biotech

4 total trials

What the Registry Record Tells You About NCT05101187

The ClinicalTrials.gov registry entry for NCT05101187 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 225 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is F2G Biotech, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Invasive Aspergillosis appearing as the primary indexed condition, and to 2 interventions - of which Olorofim is the first listed.

NCT05101187 reports 20 study locations spanning 15 distinct geographic areas - top geographies include California, Maryland, Minnesota.

Frequently Asked Questions

What is clinical trial NCT05101187 about?

NCT05101187 is a clinical study titled "Olorofim Aspergillus Infection Study". The purpose of this study is to compare treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with IFD caused by proven IA or probable lower respiratory tract disease Aspergillus species (invasive aspergillosis, IA).

What is the current status of trial NCT05101187?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 225 participants. The study started on 2022-03-31. Estimated completion is 2026-11-01.

What conditions does trial NCT05101187 study?

This clinical trial studies the following conditions: Invasive Aspergillosis.

What interventions are being tested in trial NCT05101187?

The interventions under investigation include: Olorofim (DRUG), AmBisome® (DRUG).

Who is sponsoring clinical trial NCT05101187?

This trial is sponsored by F2G Biotech, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05101187 being conducted?

This trial has 20 study locations across Alabama, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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