Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
AkLief Evaluation in Acne-induced Post-Inflammatory Hyperpigmentation
NCT05089708 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to evaluate the efficacy and safety of Trifarotene 50 microgram per gram (mcg/g) cream compared to its vehicle cream in the treatment of moderate acne vulgaris with risk of acne-induced post inflammatory hyperpigmentation (PIH) after 24 weeks of treatment in facial acne participants
Conditions Studied
Interventions
- DRUG Trifarotene Cream
- DRUG Trifarotene Vehicle Cream
Study Locations (20)
California
- Galderma Investigational Site #8636 — Fountain Valley
- Galderma Investigational Site #8224 — Fremont
- Galderma Investigational Site #8358 — San Diego
- Galderma Investigational Site #9955 — San Diego
Florida
- Galderma Investigational Site #7012 — Lutz
- Galderma Investigational Site #8184 — Maitland
- Galderma Investigational Site #8764 — Tampa
New York
- Galderma Investigational Site #8620 — New York
- Galderma Investigational Site #9956 — New York
- Galderma Investigational Site #9949 — New York
Louisiana
- Galderma Investigational Site #9952 — Baton Rouge
- Galderma Investigational Site #8606 — New Orleans
Maryland
- Galderma Investigational Site #8012 — Glenn Dale
- Galderma Investigational Site #9948 — Hyattsville
Indiana
- Galderma Investigational Site #9950 — Evansville
Michigan
- Galderma Investigational Site #8554 — Detroit
Nevada
- Galderma Investigational Site #8108 — Las Vegas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 123 participants |
| Start Date | 2021-12-22 |
| Est. Completion | 2022-12-15 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05089708
The ClinicalTrials.gov registry entry for NCT05089708 describes a study currently listed as completed. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 123 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Galderma R&D, which has 49 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Acne Vulgaris appearing as the primary indexed condition, and to 2 interventions — of which Trifarotene Cream is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05089708 reports 20 study locations spanning 11 distinct geographic areas — top geographies include California, Florida, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05089708 about?
NCT05089708 is a clinical study titled "AkLief Evaluation in Acne-induced Post-Inflammatory Hyperpigmentation". The purpose of this study is to evaluate the efficacy and safety of Trifarotene 50 microgram per gram (mcg/g) cream compared to its vehicle cream in the treatment of moderate acne vulgaris with risk of acne-induced post inflammatory hyperpigmentation (PIH) after 24 weeks of treatment in facial acne ...
What is the current status of trial NCT05089708?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 123 participants. The study started on 2021-12-22. Estimated completion is 2022-12-15.
What conditions does trial NCT05089708 study?
This clinical trial studies the following conditions: Acne Vulgaris. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05089708?
The interventions under investigation include: Trifarotene Cream (DRUG), Trifarotene Vehicle Cream (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05089708?
This trial is sponsored by Galderma R&D, which has 49 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05089708 being conducted?
This trial has 20 study locations across California, Florida, Indiana, Louisiana, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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