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NCT05063409 · ClinicalTrials.gov registry record · NA
Transfusion Ratio of Fresh Frozen Plasma (FFP) to Packed Red Blood Cell (PRBC) During Burn Excision and Grafting
A NA study, sponsored by Shriners Hospitals for Children.
- Completed
- Registry status
- NA
- Development phase
- 72
- Enrollment target
NCT05063409: Completed NA study, sponsored by Shriners Hospitals for Children.
NCT05063409 is a NA study that has completed, run by Shriners Hospitals for Children. The registered enrollment target is 72 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05063409, a NA study, has completed, sponsored by Shriners Hospitals for Children.
- COMPLETED
- Registry status
- NA
- Development phase
- 72 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if burn injured patients who receive blood transfusions in the operating room have better outcomes when given transfusions at a set ratio (1:1)of PRBC to FFP. Traditionally, patients that need blood transfusions during surgery are given mostly packed red blood cells (PRBC) and some fresh frozen plasma (FFP). This is usually about 1:4 ratio of FFP to PRBC. In this study, we will compare this traditional approach (1:4) to a 1:1 ratio of FFP to PRBC during the operative period. The hypothesis of the study is that the use of FFP/PRBC ratio of 1:1, compared to a ratio of 1:4 will result in a(n) 1. decrease in the amount of blood transfused in the operating room 2. decrease in the amount of blood transfused during hospitalization 3. improvement in coagulation parameters (PT/PTT, INR, antithrombin III, Protein C and Fibrinogen in the operative period (from operation start to 12 hours post operatively) and at 24 hours postoperatively 4. decrease the hospital length of stay, lung dysfunction, infections, and mortality
Primary Outcome
All transfusions during the operative period and entire hospitalization will be documented
Interventions
- OTHER Treatment
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2010-09 |
| Est. Completion | 2020-02-28 |
| Phase | NA |
What the finished NCT05063409 record still lists
NCT05063409 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which Treatment is the first listed.
NCT05063409 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05063409 about?
NCT05063409 is a clinical study titled "Transfusion Ratio of Fresh Frozen Plasma (FFP) to Packed Red Blood Cell (PRBC) During Burn Excision and Grafting". The purpose of this study is to determine if burn injured patients who receive blood transfusions in the operating room have better outcomes when given transfusions at a set ratio (1:1)of PRBC to FFP. Traditionally, patients that need blood transfusions during surgery are given mostly packed red bl...
What is the current status of trial NCT05063409?
This trial is currently completed. It is a NA study. The enrollment target is 72 participants. The study started on 2010-09. Estimated completion is 2020-02-28.
What interventions are being tested in trial NCT05063409?
The interventions under investigation include: Treatment (OTHER).
Who is sponsoring clinical trial NCT05063409?
This trial is sponsored by Shriners Hospitals for Children, which has 40 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05063409's enrollment target sits among peer trials
72 1089th of 2000 higher than 899 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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