Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05063409 · ClinicalTrials.gov registry record · NA
Transfusion Ratio of Fresh Frozen Plasma (FFP) to Packed Red Blood Cell (PRBC) During Burn Excision and Grafting
A NA study, sponsored by Shriners Hospitals for Children.
- Completed
- Registry status
- NA
- Development phase
- 72
- Enrollment target
NCT05063409 is a NA study that has completed, run by Shriners Hospitals for Children. The registered enrollment target is 72 participants.
The verdict
NCT05063409, a NA study, has completed, sponsored by Shriners Hospitals for Children.
- COMPLETED
- Registry status
- NA
- Development phase
- 72 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if burn injured patients who receive blood transfusions in the operating room have better outcomes when given transfusions at a set ratio (1:1)of PRBC to FFP. Traditionally, patients that need blood transfusions during surgery are given mostly packed red blood cells (PRBC) and some fresh frozen plasma (FFP). This is usually about 1:4 ratio of FFP to PRBC. In this study, we will compare this traditional approach (1:4) to a 1:1 ratio of FFP to PRBC during the operative period. The hypothesis of the study is that the use of FFP/PRBC ratio of 1:1, compared to a ratio of 1:4 will result in a(n) 1. decrease in the amount of blood transfused in the operating room 2. decrease in the amount of blood transfused during hospitalization 3. improvement in coagulation parameters (PT/PTT, INR, antithrombin III, Protein C and Fibrinogen in the operative period (from operation start to 12 hours post operatively) and at 24 hours postoperatively 4. decrease the hospital length of stay, lung dysfunction, infections, and mortality
Interventions
- OTHER Treatment
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2010-09 |
| Est. Completion | 2020-02-28 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05063409
The ClinicalTrials.gov registry entry for NCT05063409 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Shriners Hospitals for Children, which has 40 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Treatment is the first listed.
NCT05063409 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05063409 about?
NCT05063409 is a clinical study titled "Transfusion Ratio of Fresh Frozen Plasma (FFP) to Packed Red Blood Cell (PRBC) During Burn Excision and Grafting". The purpose of this study is to determine if burn injured patients who receive blood transfusions in the operating room have better outcomes when given transfusions at a set ratio (1:1)of PRBC to FFP. Traditionally, patients that need blood transfusions during surgery are given mostly packed red bl...
What is the current status of trial NCT05063409?
This trial is currently completed. It is a NA study. The enrollment target is 72 participants. The study started on 2010-09. Estimated completion is 2020-02-28.
What interventions are being tested in trial NCT05063409?
The interventions under investigation include: Treatment (OTHER).
Who is sponsoring clinical trial NCT05063409?
This trial is sponsored by Shriners Hospitals for Children, which has 40 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.