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NCT04946526 · ClinicalTrials.gov registry record · NA

Broccoli Sulforaphane Bioavailability With Mustard

A NA study of Sulforaphane Bioavailability, sponsored by Appalachian State University.

Completed
Registry status
NA
Development phase
16
Enrollment target
1
Study location

NCT04946526 is a NA study of Sulforaphane Bioavailability that has completed, run by Appalachian State University. The registered enrollment target is 16 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT04946526, a NA study of Sulforaphane Bioavailability, has completed, sponsored by Appalachian State University.

COMPLETED
Registry status
NA
Development phase
16 participants
Enrollment target
1
Study location

Study Summary

We know that broccoli is a vegetable that is associated with a number of health benefits and is a good choice in a healthy diet. Researchers at major universities, including Johns Hopkins University, have identified nutrients in broccoli that have specific health benefits such as improving antioxidant protection. One of these nutrients is called glucoraphanin (GR). However, in order for GR to deliver health benefits in the human body, it first has to be converted to its active form, sulforaphane (SF). This conversion can happen one of two ways. GR can be converted to SF by our gut bacteria (the microbiota) or it can be converted to SF by an enzyme called myrosinase that is naturally occurring in certain plants, including mustard (the same mustard that is used to make table mustard spread and mayonnaise). The purpose of the present study is to test in healthy human volunteers the oral bioavailability (absorption) of GR in broccoli seed extract (BSE) with or without the presence of active plant myrosinase in mustard seed powder (MSP) delivered in a nutritional supplement.

Interventions

  • DIETARY_SUPPLEMENT Broccoli seed extract
  • DIETARY_SUPPLEMENT Broccoli seed extract with mustard seed powder

Study Locations (1)

North Carolina

  • Appalachian State University Human Performance Lab, North Carolina Research Campus - Kannapolis

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2022-06-01
Est. Completion 2022-09-30
Phase NA

Sponsor

Appalachian State University

37 total trials

What the Registry Record Tells You About NCT04946526

The ClinicalTrials.gov registry entry for NCT04946526 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Appalachian State University, which has 37 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Sulforaphane Bioavailability appearing as the primary indexed condition, and to 2 interventions - of which Broccoli seed extract is the first listed.

NCT04946526 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT04946526 about?

NCT04946526 is a clinical study titled "Broccoli Sulforaphane Bioavailability With Mustard". We know that broccoli is a vegetable that is associated with a number of health benefits and is a good choice in a healthy diet. Researchers at major universities, including Johns Hopkins University, have identified nutrients in broccoli that have specific health benefits such as improving antioxida...

What is the current status of trial NCT04946526?

This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2022-06-01. Estimated completion is 2022-09-30.

What conditions does trial NCT04946526 study?

This clinical trial studies the following conditions: Sulforaphane Bioavailability.

What interventions are being tested in trial NCT04946526?

The interventions under investigation include: Broccoli seed extract (DIETARY_SUPPLEMENT), Broccoli seed extract with mustard seed powder (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT04946526?

This trial is sponsored by Appalachian State University, which has 37 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04946526 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.