Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 2

Study of VIB7734 for the Treatment of Moderate to Severely Active SLE

NCT04925934 · View on ClinicalTrials.gov ↗

Study Summary

A Phase 2 Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of VIB7734 for the Treatment of Moderate to Severely Active Systemic Lupus Erythematosus in approximately 195 participants. The study duration will be 48 weeks, with a safety follow-up through week 56.There will be 3 parallel arms - 2 active treatment and 1 placebo.

Interventions

  • OTHER Placebo
  • DRUG VIB7734

Study Locations (20)

Florida

  • Clinical Research of West Florida Inc - Clearwater — Clearwater
  • Millennium Research — Ormond Beach
  • IRIS Research and Development LLC — Plantation
  • Clinical Research of West Florida Inc - Tampa — Tampa

Texas

  • Tekton Research Inc — Austin
  • Precision Comprehensive Clinical Research Solutions — Colleyville
  • Metroplex Clinical Research Center — Dallas
  • Southwest Rheumatology Research, LLC — Mesquite

New York

  • NYU Langone Ambulatory Care Brooklyn Heights — Brooklyn
  • Feinstein Institute For Medical Research — Manhasset
  • SUNY Upstate Medical Center — Syracuse

Buenos Aires

  • Consultorios Médicos Dr. Doreski — Ciudad Autónoma de Buenos Aires
  • Clínica Adventista Belgrano — Estomba
  • Framingham Centro Médico — La Plata

California

  • Inland Rheumatology Clinical Trials Incorporated — Upland

Georgia

  • Emory University School of Medicine — Atlanta

Kentucky

  • Bluegrass Community Research Inc — Lexington

North Carolina

  • DJL Clinical Research — Charlotte

Trial Details

FieldValue
Enrollment Target 214 participants
Start Date 2021-05-28
Est. Completion 2023-06-09
Phase Phase 2

Sponsor

Amgen

266 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04925934

The ClinicalTrials.gov registry entry for NCT04925934 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 214 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Amgen, which has 266 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Lupus Erythematosus, Systemic appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04925934 reports 20 study locations spanning 10 distinct geographic areas — top geographies include Florida, Texas, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04925934 about?

NCT04925934 is a clinical study titled "Study of VIB7734 for the Treatment of Moderate to Severely Active SLE". A Phase 2 Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of VIB7734 for the Treatment of Moderate to Severely Active Systemic Lupus Erythematosus in approximately 195 participants. The study duration will be 48 weeks, with a safety follow-up through week 56.There will be 3 pa...

What is the current status of trial NCT04925934?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 214 participants. The study started on 2021-05-28. Estimated completion is 2023-06-09.

What conditions does trial NCT04925934 study?

This clinical trial studies the following conditions: Lupus Erythematosus, Systemic. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04925934?

The interventions under investigation include: Placebo (OTHER), VIB7734 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04925934?

This trial is sponsored by Amgen, which has 266 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04925934 being conducted?

This trial has 20 study locations across California, Florida, Georgia, Kentucky, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial