Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04883138 · ClinicalTrials.gov registry record · Phase 1

Recombinant Hyperimmune Polyclonal Antibody (GIGA-2050) in COVID-19 Patients

A Phase 1 study, sponsored by GigaGen.

Terminated
Registry status
Phase 1
Development phase
3
Enrollment target

NCT04883138: Clinical Trial Phase 1 study, sponsored by GigaGen.

NCT04883138 is a Phase 1 study that was terminated before completion, run by GigaGen. The registered enrollment target is 3 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04883138, a Phase 1 study, was terminated before completion, sponsored by GigaGen.

TERMINATED
Registry status
Phase 1
Development phase
3 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety and tolerability of single ascending IV dose administrations of GIGA-2050 in patients hospitalized with COVID-19.

Primary Outcome

Frequency of TEAEs graded by the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 5.0

Interventions

  • DRUG GIGA-2050

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2021-05-24
Est. Completion 2022-01-11
Phase Phase 1
GigaGen

3 total trials

Why NCT04883138 stopped before completion

NCT04883138 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 1 intervention - of which GIGA-2050 is the first listed.

NCT04883138 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04883138 about?

NCT04883138 is a clinical study titled "Recombinant Hyperimmune Polyclonal Antibody (GIGA-2050) in COVID-19 Patients". The purpose of this study is to evaluate the safety and tolerability of single ascending IV dose administrations of GIGA-2050 in patients hospitalized with COVID-19.

What is the current status of trial NCT04883138?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2021-05-24. Estimated completion is 2022-01-11.

What interventions are being tested in trial NCT04883138?

The interventions under investigation include: GIGA-2050 (DRUG).

Who is sponsoring clinical trial NCT04883138?

This trial is sponsored by GigaGen, which has 3 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04883138's enrollment target sits among peer trials

3 1999th of 2000 higher than 1 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04883138, the US trial registry maintained by the National Library of Medicine. NCT04883138 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.