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NCT04862468 · ClinicalTrials.gov registry record · Phase 2

Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT

A Phase 2 study of Iliofemoral; Thrombosis and Thrombosis, Deep Vein, sponsored by Mercator MedSystems.

Recruiting
Registry status
Phase 2
Development phase
80
Enrollment target
17
Study locations

NCT04862468: Recruiting Phase 2 study of Iliofemoral; Thrombosis and Thrombosis, Deep Vein, sponsored by Mercator MedSystems.

NCT04862468 is a Phase 2 study of Iliofemoral; Thrombosis and Thrombosis, Deep Vein that is actively recruiting participants, run by Mercator MedSystems. The registered enrollment target is 80 participants. The trial reports 17 study locations across 14 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04862468, a Phase 2 study of Iliofemoral; Thrombosis and Thrombosis, Deep Vein, is actively recruiting participants, sponsored by Mercator MedSystems.

RECRUITING
Registry status
Phase 2
Development phase
80 participants
Enrollment target
17
Study locations

Study Summary

This is a study of a medical procedure that utilizes a commercially available catheter (the Bullfrog® Micro-Infusion Device) to locally deliver a commercially available anti-inflammatory drug (dexamethasone sodium phosphate injection) around the deep veins after DVT recanalization, where DVT symptoms were present for up to 14 days prior to recanalization. The goal of the study is to see if local anti-inflammation helps prevent re-thrombosis of the blood vessel and improvement in symptoms for up to 24 months after the initial DVT recanalization procedure.

Interventions

  • COMBINATION_PRODUCT Perivascular dexamethasone
  • COMBINATION_PRODUCT Perivascular sham

Study Locations (17)

Florida

  • HCA Florida JFK Hospital - Atlantis
  • Baptist Health - Jacksonville
  • University of South Florida - Tampa

Other

  • Galway University Hospital - Galway
  • Guy's and St. Thomas Hospital - London

California

  • Providence St. Joseph Hospital - Orange

Connecticut

  • Vascular Care Connecticut - Darien

Georgia

  • Piedmont Heart Institute - Atlanta

Louisiana

  • CIS Clinical Research - Houma

Maryland

  • Medstar Health Research Institute - Hyattsville

New Jersey

  • Englewood Health - Englewood

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2021-10-29
Est. Completion 2028-02-01
Phase Phase 2

Sponsor

Mercator MedSystems

7 total trials

What the Registry Record Tells You About NCT04862468

The ClinicalTrials.gov registry entry for NCT04862468 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mercator MedSystems, which has 7 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Iliofemoral; Thrombosis appearing as the primary indexed condition, and to 2 interventions - of which Perivascular dexamethasone is the first listed.

NCT04862468 reports 17 study locations spanning 14 distinct geographic areas - top geographies include Florida, Other, California.

Frequently Asked Questions

What is clinical trial NCT04862468 about?

NCT04862468 is a clinical study titled "Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT". This is a study of a medical procedure that utilizes a commercially available catheter (the Bullfrog® Micro-Infusion Device) to locally deliver a commercially available anti-inflammatory drug (dexamethasone sodium phosphate injection) around the deep veins after DVT recanalization, where DVT symptom...

What is the current status of trial NCT04862468?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2021-10-29. Estimated completion is 2028-02-01.

What conditions does trial NCT04862468 study?

This clinical trial studies the following conditions: Iliofemoral; Thrombosis, Thrombosis, Deep Vein.

What interventions are being tested in trial NCT04862468?

The interventions under investigation include: Perivascular dexamethasone (COMBINATION_PRODUCT), Perivascular sham (COMBINATION_PRODUCT).

Who is sponsoring clinical trial NCT04862468?

This trial is sponsored by Mercator MedSystems, which has 7 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04862468 being conducted?

This trial has 17 study locations across California, Connecticut, Florida, Georgia, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.