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NCT04846959 · ClinicalTrials.gov registry record

Study to Evaluate Pregnancy Outcomes in Risankizumab Exposed Pregnancies Relative to Those Non-risankizumab Exposed Pregnancies in Women With FDA Approved Indications

A clinical trial of Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, or Other Conditions for Which Risankizumab is an FDA-approved Treatment, sponsored by AbbVie.

Recruiting
Registry status
818
Enrollment target
2
Study locations

NCT04846959 is a study of Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, or Other Conditions for Which Risankizumab is an FDA-approved Treatment that is actively recruiting participants, run by AbbVie. The registered enrollment target is 818 participants. The trial reports 2 study locations across 1 state.

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The verdict

NCT04846959, a study of Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, or Other Conditions for Which Risankizumab is an FDA-approved Treatment, is actively recruiting participants, sponsored by AbbVie.

RECRUITING
Registry status
818 participants
Enrollment target
2
Study locations

Study Summary

The objective of this registry is to compare outcomes of risankizumab-exposed pregnancies with those of pregnancies that were not exposed to risankizumab among women with plaque psoriasis, psoriatic arthritis (PsA), Crohn's disease (CD), or other conditions for which risankizumab is an FDA-approved treatment. The registry is designed to estimate the association between risankizumab and maternal, fetal, and infant outcomes by comparing the prevalence rates of these outcomes in the exposed and unexposed populations. Approximately 818 female participants with pregnancy will be enrolled (409 participants exposed to risankizumab and 409 without exposure) at multiple sites across the United States. Participants will not receive risankizumab as part of this study. Maternal and fetal outcomes during pregnancy for female participants who received risankizumab or other treatment will be followed for and up to 1 year after delivery There may be a higher burden for participants in this study compared to standard of care. Participants will attend visits determined by HCPs during the study at a hospital or clinic. The pregnancy outcomes including side effects will be collected during routine clinical care.

Interventions

  • DRUG Risankizumab
  • DRUG Comparator

Study Locations (2)

North Carolina

  • Evidera, a PPD Business Unit /ID# 238688 - Morrisville
  • PPD Development, LP /ID# 232134 - Wilmington

Trial Details

FieldValue
Enrollment Target 818 participants
Start Date 2021-07-30
Est. Completion 2032-06

Sponsor

AbbVie

526 total trials

What the Registry Record Tells You About NCT04846959

The ClinicalTrials.gov registry entry for NCT04846959 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 818 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AbbVie, which has 526 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, or Other Conditions for Which Risankizumab is an FDA-approved Treatment appearing as the primary indexed condition, and to 2 interventions - of which Risankizumab is the first listed.

NCT04846959 reports 2 study locations spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT04846959 about?

NCT04846959 is a clinical study titled "Study to Evaluate Pregnancy Outcomes in Risankizumab Exposed Pregnancies Relative to Those Non-risankizumab Exposed Pregnancies in Women With FDA Approved Indications". The objective of this registry is to compare outcomes of risankizumab-exposed pregnancies with those of pregnancies that were not exposed to risankizumab among women with plaque psoriasis, psoriatic arthritis (PsA), Crohn's disease (CD), or other conditions for which risankizumab is an FDA-approved ...

What is the current status of trial NCT04846959?

This trial is currently recruiting. The enrollment target is 818 participants. The study started on 2021-07-30. Estimated completion is 2032-06.

What conditions does trial NCT04846959 study?

This clinical trial studies the following conditions: Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, or Other Conditions for Which Risankizumab is an FDA-approved Treatment.

What interventions are being tested in trial NCT04846959?

The interventions under investigation include: Risankizumab (DRUG), Comparator (DRUG).

Who is sponsoring clinical trial NCT04846959?

This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04846959 being conducted?

This trial has 2 study locations across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.