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NCT04792697 · ClinicalTrials.gov registry record · NA
Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens
A NA study of Delayed Sleep Phase Syndrome, sponsored by University of Pittsburgh.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT04792697: Recruiting NA study of Delayed Sleep Phase Syndrome, sponsored by University of Pittsburgh.
NCT04792697 is a NA study of Delayed Sleep Phase Syndrome that is actively recruiting participants, run by University of Pittsburgh. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04792697, a NA study of Delayed Sleep Phase Syndrome, is actively recruiting participants, sponsored by University of Pittsburgh.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their sleep/wake patterns paired with early school start times. Many studies find that this increases the risk for substance use (SU). However, what impact circadian rhythm and sleep disruption either together or independently have on the neuronal circuitry that controls reward and cognition, or if there are interventions that might help to modify these disruptions is unknown. Project 2 (P2) of the CARRS center will test an innovative and mechanistic model of brain circuitry that uses multi-method approaches, takes a developmental perspective, and incorporates key sleep and reward constructs.
Primary Outcome
Total Sleep Time as determined by wrist actigraphy data \& sleep diaries (averaged across weekdays during 2 weeks at T1 and 2 weeks at T2)
Conditions Studied
Interventions
- OTHER Increase morning bright light
- OTHER Decrease evening blue light
- BEHAVIORAL Sleep Scheduling
- BEHAVIORAL Monitor sleep, mood, and substance use
Study Locations (1)
Pennsylvania
- Western Psychiatric Hospital - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2021-05-01 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What NCT04792697 shows while recruiting
NCT04792697 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Delayed Sleep Phase Syndrome appearing as the primary indexed condition, and to 4 interventions - of which Increase morning bright light is the first listed.
NCT04792697 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT04792697 about?
NCT04792697 is a clinical study titled "Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens". Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their sleep/wake patterns paired with early school start times. Many studies fin...
What is the current status of trial NCT04792697?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2021-05-01. Estimated completion is 2026-06-30.
What conditions does trial NCT04792697 study?
This clinical trial studies the following conditions: Delayed Sleep Phase Syndrome.
What interventions are being tested in trial NCT04792697?
The interventions under investigation include: Increase morning bright light (OTHER), Decrease evening blue light (OTHER), Sleep Scheduling (BEHAVIORAL), Monitor sleep, mood, and substance use (BEHAVIORAL).
Who is sponsoring clinical trial NCT04792697?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04792697 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Delayed Sleep Phase Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04792697's enrollment target sits among peer trials
100 840th of 2000 higher than 1,081 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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