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NCT04759898 · ClinicalTrials.gov registry record
Direct Measurement of Motor Cortical Responses to tDCS
A clinical trial, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- 20
- Enrollment target
NCT04759898: Completed study, sponsored by Medical University of South Carolina.
NCT04759898 is a clinical trial that has completed, run by Medical University of South Carolina. The registered enrollment target is 20 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04759898 has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- 20 participants
- Enrollment target
Study Summary
Transcranial direct current stimulation (tDCS) has shown the potential to improve symptoms in patients with movement deficits, such as Parkinson's disease and chronic stroke. However, the effects of tDCS have so far not been proven on a wider scale due to lack of knowledge regarding exactly how tDCS works. This has limited the adoption of this potentially useful therapy for patients with Parkinson's disease, chronic stroke and other conditions affecting movement. The investigators hypothesize that by studying the effects of tDCS in subjects performing a motor task, the brain signals mediating improvements in motor control will be identified. The investigators will use both noninvasive and invasive methods to explore this hypothesis. The investigators expect this combined approach to broaden understanding of tDCS application in conditions affecting movement and possibly lead to therapeutic advances in these populations.
Primary Outcome
Primary motor cortex (PriMC) beta-band (13-30 Hz) spectral power was measured using subdural electrocorticography (sECoG) in patients with Parkinson's disease undergoing deep brain stimulation surgery. Spectral power was analyzed during the movement preparation phase of a cued arm-reaching task. The outcome represents the change in beta-band spectral power during anodal transcranial direct current stimulation (tDCS) relative to pre-stimulation baseline, averaged across task trials for each parti
Interventions
- DEVICE transcranial direct current stimulation (invasive recording)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2021-01-01 |
| Est. Completion | 2025-01-01 |
What the finished NCT04759898 record still lists
NCT04759898 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which transcranial direct current stimulation (invasive recording) is the first listed.
NCT04759898 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04759898 about?
NCT04759898 is a clinical study titled "Direct Measurement of Motor Cortical Responses to tDCS". Transcranial direct current stimulation (tDCS) has shown the potential to improve symptoms in patients with movement deficits, such as Parkinson's disease and chronic stroke. However, the effects of tDCS have so far not been proven on a wider scale due to lack of knowledge regarding exactly how tDCS...
What is the current status of trial NCT04759898?
This trial is currently completed. The enrollment target is 20 participants. The study started on 2021-01-01. Estimated completion is 2025-01-01.
What interventions are being tested in trial NCT04759898?
The interventions under investigation include: transcranial direct current stimulation (invasive recording) (DEVICE).
Who is sponsoring clinical trial NCT04759898?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
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