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NCT04738149 · ClinicalTrials.gov registry record · Early Phase 1

Effect of Microneedling, Bimatoprost and Excimer in Vitiligo Treatment

A Early Phase 1 study of Vitiligo, sponsored by Medical University of South Carolina.

Completed
Registry status
Early Phase 1
Development phase
4
Enrollment target
1
Study location

NCT04738149 is a Early Phase 1 study of Vitiligo that has completed, run by Medical University of South Carolina. The registered enrollment target is 4 participants, below the 1,124-participant average among 15 other Vitiligo trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04738149, a Early Phase 1 study of Vitiligo, has completed, sponsored by Medical University of South Carolina.

COMPLETED
Registry status
Early Phase 1
Development phase
4 participants
Enrollment target
1
Study location

Study Summary

The purpose of this research is to treat vitiligo with a topical PGF2α, microneedling and excimer laser. The goal is to have greater repigmentation than the standard of care (excimer) after 12 weeks of treatment. The study is a pilot, split study meaning the patient will receive one experimental and one standard of care treatment on symmetric lesions of similar location, geometrics and size. Enrolled subjects will present biweekly to clinic on the same two days for twelve weeks. One lesion will be treated with microneedling, topical PGF2α and calibrated excimer laser, while the parallel lesion will be excimer laser alone. Physical exam, photographs, and a review of of the subjects medical records will occur in the study. Changes in size, appearance, and adverse events will be monitored throughout the study. The patient will also agree to close up photographs of their lesions throughout the study. The possible benefit of joining this study is that the treatment received may be more effective than the other study treatment or then other available treatments for vitiligo, although this cannot be guaranteed.

Conditions Studied

Interventions

  • DRUG Bimatoprost
  • DEVICE Excimer laser
  • DEVICE Microneedling with a dermaroller

Study Locations (1)

South Carolina

  • Medical University of South Carolina - Charleston

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2021-11-02
Est. Completion 2022-05-15
Phase Early Phase 1

What the Registry Record Tells You About NCT04738149

The ClinicalTrials.gov registry entry for NCT04738149 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,124-participant average among 15 other Vitiligo trials with a reported enrollment target (100% lower). The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Vitiligo appearing as the primary indexed condition, and to 3 interventions - of which Bimatoprost is the first listed.

NCT04738149 reports 1 study location spanning 1 distinct geographic area - top geographies include South Carolina.

Frequently Asked Questions

What is clinical trial NCT04738149 about?

NCT04738149 is a clinical study titled "Effect of Microneedling, Bimatoprost and Excimer in Vitiligo Treatment". The purpose of this research is to treat vitiligo with a topical PGF2α, microneedling and excimer laser. The goal is to have greater repigmentation than the standard of care (excimer) after 12 weeks of treatment. The study is a pilot, split study meaning the patient will receive one experimental an...

What is the current status of trial NCT04738149?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 4 participants. The study started on 2021-11-02. Estimated completion is 2022-05-15.

What conditions does trial NCT04738149 study?

This clinical trial studies the following conditions: Vitiligo.

What interventions are being tested in trial NCT04738149?

The interventions under investigation include: Bimatoprost (DRUG), Excimer laser (DEVICE), Microneedling with a dermaroller (DEVICE).

Who is sponsoring clinical trial NCT04738149?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04738149 being conducted?

This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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