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NCT04738149 · ClinicalTrials.gov registry record · Early Phase 1
Effect of Microneedling, Bimatoprost and Excimer in Vitiligo Treatment
A Early Phase 1 study of Vitiligo, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 4
- Enrollment target
- 1
- Study location
NCT04738149: Completed Early Phase 1 study of Vitiligo, sponsored by Medical University of South Carolina.
NCT04738149 is a Early Phase 1 study of Vitiligo that has completed, run by Medical University of South Carolina. The registered enrollment target is 4 participants, below the 1,124-participant average among 15 other Vitiligo trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04738149, a Early Phase 1 study of Vitiligo, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 4 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research is to treat vitiligo with a topical PGF2α, microneedling and excimer laser. The goal is to have greater repigmentation than the standard of care (excimer) after 12 weeks of treatment. The study is a pilot, split study meaning the patient will receive one experimental and one standard of care treatment on symmetric lesions of similar location, geometrics and size. Enrolled subjects will present biweekly to clinic on the same two days for twelve weeks. One lesion will be treated with microneedling, topical PGF2α and calibrated excimer laser, while the parallel lesion will be excimer laser alone. Physical exam, photographs, and a review of of the subjects medical records will occur in the study. Changes in size, appearance, and adverse events will be monitored throughout the study. The patient will also agree to close up photographs of their lesions throughout the study. The possible benefit of joining this study is that the treatment received may be more effective than the other study treatment or then other available treatments for vitiligo, although this cannot be guaranteed.
Primary Outcome
A blinded outcome accessor will compare photographs of patients before and after treatment.
Conditions Studied
Interventions
- DRUG Bimatoprost
- DEVICE Excimer laser
- DEVICE Microneedling with a dermaroller
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2021-11-02 |
| Est. Completion | 2022-05-15 |
| Phase | Early Phase 1 |
What the finished NCT04738149 record still lists
NCT04738149 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,124-participant average among 15 other Vitiligo trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Vitiligo appearing as the primary indexed condition, and to 3 interventions - of which Bimatoprost is the first listed.
NCT04738149 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT04738149 about?
NCT04738149 is a clinical study titled "Effect of Microneedling, Bimatoprost and Excimer in Vitiligo Treatment". The purpose of this research is to treat vitiligo with a topical PGF2α, microneedling and excimer laser. The goal is to have greater repigmentation than the standard of care (excimer) after 12 weeks of treatment. The study is a pilot, split study meaning the patient will receive one experimental an...
What is the current status of trial NCT04738149?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 4 participants. The study started on 2021-11-02. Estimated completion is 2022-05-15.
What conditions does trial NCT04738149 study?
This clinical trial studies the following conditions: Vitiligo.
What interventions are being tested in trial NCT04738149?
The interventions under investigation include: Bimatoprost (DRUG), Excimer laser (DEVICE), Microneedling with a dermaroller (DEVICE).
Who is sponsoring clinical trial NCT04738149?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04738149 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Vitiligo
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04738149's enrollment target sits among peer trials
4 16th of 15 the lowest of 15 other Vitiligo trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Vitiligo trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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