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NCT04691375 · ClinicalTrials.gov registry record · Phase 1

A Study of PY314 in Subjects With Advanced Solid Tumors

A Phase 1 study, sponsored by Ikena Oncology.

Terminated
Registry status
Phase 1
Development phase
86
Enrollment target

NCT04691375 is a Phase 1 study that was terminated before completion, run by Ikena Oncology. The registered enrollment target is 86 participants.

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The verdict

NCT04691375, a Phase 1 study, was terminated before completion, sponsored by Ikena Oncology.

TERMINATED
Registry status
Phase 1
Development phase
86 participants
Enrollment target

Study Summary

This is an open-label, multicenter, first in human, Phase 1a/1b study of PY314 in subjects with locally advanced (unresectable) and/or metastatic solid tumors that are refractory or relapsed to standard of care (including pembrolizumab, if approved for that indication).

Interventions

  • DRUG PY314
  • DRUG Combination Therapy: PY314 + Pembrolizumab

Trial Details

FieldValue
Enrollment Target 86 participants
Start Date 2020-10-29
Est. Completion 2023-09-22
Phase Phase 1

Sponsor

Ikena Oncology

5 total trials

What the Registry Record Tells You About NCT04691375

The ClinicalTrials.gov registry entry for NCT04691375 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 86 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Ikena Oncology, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which PY314 is the first listed.

NCT04691375 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04691375 about?

NCT04691375 is a clinical study titled "A Study of PY314 in Subjects With Advanced Solid Tumors". This is an open-label, multicenter, first in human, Phase 1a/1b study of PY314 in subjects with locally advanced (unresectable) and/or metastatic solid tumors that are refractory or relapsed to standard of care (including pembrolizumab, if approved for that indication).

What is the current status of trial NCT04691375?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 86 participants. The study started on 2020-10-29. Estimated completion is 2023-09-22.

What interventions are being tested in trial NCT04691375?

The interventions under investigation include: PY314 (DRUG), Combination Therapy: PY314 + Pembrolizumab (DRUG).

Who is sponsoring clinical trial NCT04691375?

This trial is sponsored by Ikena Oncology, which has 5 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.