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A Study to Evaluate the Efficacy, Safety, and Tolerability of Brivaracetam as Monotherapy in Patients 2 to 25 Years of Age With Childhood Absence Epilepsy or Juvenile Absence Epilepsy
NCT04666610 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of the study is to test the efficacy, safety and tolerability of brivaracetam monotherapy in study participants 2 to 25 years of age inclusive with childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE).
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Brivaracetam
Study Locations (20)
Other
- N01269 400 — Tbilisi
- N01269 401 — Tbilisi
- N01269 402 — Tbilisi
- N01269 403 — Tbilisi
- N01269 405 — Tbilisi
- N01269 323 — Messina
- N01269 321 — Milan
- N01269 324 — Milan
- N01269 320 — Pavia
- N01269 322 — Roma
Florida
- N01269 111 — Miami
- N01269 101 — Tampa
- N01269 104 — Winter Park
Alabama
- N01269 115 — Birmingham
California
- N01269 105 — Orange
Colorado
- N01269 116 — Denver
Georgia
- N01269 110 — Augusta
New Jersey
- N01269 100 — New Brunswick
North Carolina
- N01269 109 — Winston-Salem
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 153 participants |
| Start Date | 2021-07-29 |
| Est. Completion | 2026-08-24 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04666610
The ClinicalTrials.gov registry entry for NCT04666610 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 153 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is UCB Biopharma SRL, which has 116 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Childhood Absence Epilepsy appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04666610 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Other, Florida, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04666610 about?
NCT04666610 is a clinical study titled "A Study to Evaluate the Efficacy, Safety, and Tolerability of Brivaracetam as Monotherapy in Patients 2 to 25 Years of Age With Childhood Absence Epilepsy or Juvenile Absence Epilepsy". The purpose of the study is to test the efficacy, safety and tolerability of brivaracetam monotherapy in study participants 2 to 25 years of age inclusive with childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE).
What is the current status of trial NCT04666610?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 153 participants. The study started on 2021-07-29. Estimated completion is 2026-08-24.
What conditions does trial NCT04666610 study?
This clinical trial studies the following conditions: Childhood Absence Epilepsy, Juvenile Absence Epilepsy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04666610?
The interventions under investigation include: Placebo (OTHER), Brivaracetam (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04666610?
This trial is sponsored by UCB Biopharma SRL, which has 116 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04666610 being conducted?
This trial has 20 study locations across Alabama, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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