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NCT04630847 · ClinicalTrials.gov registry record · Phase 1

Familial Fecal Microbiota Transplant for the Treatment of Subjects With Autism Spectrum Disorders

A Phase 1 study, sponsored by ProgenaBiome.

Not yet
Registry status
Phase 1
Development phase
10
Enrollment target

NCT04630847: Clinical Trial Phase 1 study, sponsored by ProgenaBiome.

NCT04630847 is a Phase 1 study that has not yet begun recruiting, run by ProgenaBiome. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04630847, a Phase 1 study, has not yet begun recruiting, sponsored by ProgenaBiome.

NOT YET RECRUITING
Registry status
Phase 1
Development phase
10 participants
Enrollment target

Study Summary

This is an open-label clinical trial to evaluate the benefits of familial fecal microbiota transplant following a 6-week treatment with Vancomycin in adult subjects with ASD for treatment of social deficits and language delays.

Primary Outcome

Number of participants with changes in the Autism Treatment Evaluation Checklist scores

Interventions

  • BIOLOGICAL Fecal Microbiota Transplant

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2025-12
Est. Completion 2027-07
Phase Phase 1
ProgenaBiome

8 total trials

What is known before NCT04630847 opens enrollment

NCT04630847 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 1 intervention - of which Fecal Microbiota Transplant is the first listed.

NCT04630847 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04630847 about?

NCT04630847 is a clinical study titled "Familial Fecal Microbiota Transplant for the Treatment of Subjects With Autism Spectrum Disorders". This is an open-label clinical trial to evaluate the benefits of familial fecal microbiota transplant following a 6-week treatment with Vancomycin in adult subjects with ASD for treatment of social deficits and language delays.

What is the current status of trial NCT04630847?

This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2025-12. Estimated completion is 2027-07.

What interventions are being tested in trial NCT04630847?

The interventions under investigation include: Fecal Microbiota Transplant (BIOLOGICAL).

Who is sponsoring clinical trial NCT04630847?

This trial is sponsored by ProgenaBiome, which has 8 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04630847's enrollment target sits among peer trials

10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04630847, the US trial registry maintained by the National Library of Medicine. NCT04630847 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.