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Intervention to Reduce Early (Peanut) Allergy in Children
NCT04604431 · View on ClinicalTrials.gov ↗
Study Summary
iREACH is a five-year NIH funded study aimed at assessing and improving pediatric clinician adherence to the 2017 NIAID Prevention of Peanut Allergy (PPA) Guidelines. iREACH has been developed as an electronic health record (EHR) integrated Clinical Decision Support (CDS) tool together with educational modules on the PPA guidelines to assist clinicians in implementing the 2017 NIAID PPA Guidelines. A practice-based, two-arm, cluster-randomized clinical trial will evaluate the effectiveness of iREACH in increasing pediatric clinician adherence to the PPA Guidelines and explore the end-goal of reducing peanut allergy incidence by age 2.5 years in the intervention vs control group. This study has the potential to: 1) provide evidence regarding the effectiveness of iREACH in promoting clinical processes and outcomes related to the PPA Guidelines, 2) provide important insight about practice-based implementation of PPA Guidelines by pediatric clinicians, allergists and caregivers, and 3) facilitate rapid, widespread implementation of PPA Guidelines and reduce peanut allergy incidence across the US.
Conditions Studied
Interventions
- OTHER iREACH CDS Tool
Study Locations (20)
Illinois
- Pediatric Associates of Arlington Heights, SC-PEDIATRUST — Arlington Heights
- OSF Medical Group Pediatrics Bloomington — Bloomington
- Child and Adolescent Health Associates — Chicago
- Northwestern Children's Practice — Chicago
- Streeterville Pediatrics — Chicago
- Erie Family Health Centers - Erie Teen and Young Adult Health Center — Chicago
- Erie Family Health Centers - West Town — Chicago
- Erie Family Health Centers - Helping Hands - Foster — Chicago
- Lurie Children's Primary Care Town & Country Pediatrics — Chicago
- Near North Health Services Corporation — Chicago
- Children's Health Associates — Chicago
- Lakeview Pediatrics — Chicago
- OSF Medical Group Pediatrics Danville — Danville
- Erie Family Health Centers - Evanston — Evanston
- Lurie Children's Primary Care Chicago Area Pediatrics — Evanston
- OSF Medical Group Pediatrics Godfrey — Godfrey
- Pediatric Partners, SC-PEDIATRUST — Highland Park
- Bedrose Pediatrics — Hoffman Estates
- Lake Shore Pediatrics, SC-PEDIATRUST — Libertyville
- OSF Medical Group (MG)-Morton Pediatrics — Morton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2020-11-04 |
| Est. Completion | 2025-12-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04604431
The ClinicalTrials.gov registry entry for NCT04604431 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Ann & Robert H Lurie Children's Hospital of Chicago, which has 69 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Food Allergy in Infants appearing as the primary indexed condition, and to 1 intervention — of which iREACH CDS Tool is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04604431 reports 20 study locations spanning 1 distinct geographic area — top geographies include Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04604431 about?
NCT04604431 is a clinical study titled "Intervention to Reduce Early (Peanut) Allergy in Children". iREACH is a five-year NIH funded study aimed at assessing and improving pediatric clinician adherence to the 2017 NIAID Prevention of Peanut Allergy (PPA) Guidelines. iREACH has been developed as an electronic health record (EHR) integrated Clinical Decision Support (CDS) tool together with educati...
What is the current status of trial NCT04604431?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2020-11-04. Estimated completion is 2025-12-31.
What conditions does trial NCT04604431 study?
This clinical trial studies the following conditions: Food Allergy in Infants, Food Allergy Peanut. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04604431?
The interventions under investigation include: iREACH CDS Tool (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04604431?
This trial is sponsored by Ann & Robert H Lurie Children's Hospital of Chicago, which has 69 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04604431 being conducted?
This trial has 20 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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