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Predicting BCG Response
NCT04564781 · View on ClinicalTrials.gov ↗
Study Summary
To date, there are no diagnostics capable of predicting treatment response to intravesical BCG. Because of this severe limitation, nearly 50% of patients treated with BCG fail therapy and will a) require additional intravesical therapy or b) require cystectomy. A urine-based diagnostic that possesses the potential to accurately identify patients who will respond favorably to intravesical BCG is desperately needed.
Conditions Studied
Study Locations (5)
California
- Cedars-Sinai Medical Center — Los Angeles
- UCLA — Los Angeles
- UCSF — San Francisco
Texas
- University of Texas Southwestern — Dallas
Kyoto
- Kyoto University — Kyoto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2020-09-18 |
| Est. Completion | 2030-02 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04564781
The ClinicalTrials.gov registry entry for NCT04564781 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Cedars-Sinai Medical Center, which has 360 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Bladder Cancer appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04564781 reports 5 study locations spanning 3 distinct geographic areas — top geographies include California, Texas, Kyoto. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04564781 about?
NCT04564781 is a clinical study titled "Predicting BCG Response". To date, there are no diagnostics capable of predicting treatment response to intravesical BCG. Because of this severe limitation, nearly 50% of patients treated with BCG fail therapy and will a) require additional intravesical therapy or b) require cystectomy. A urine-based diagnostic that possesse...
What is the current status of trial NCT04564781?
This trial is currently recruiting. The enrollment target is 400 participants. The study started on 2020-09-18. Estimated completion is 2030-02.
What conditions does trial NCT04564781 study?
This clinical trial studies the following conditions: Bladder Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT04564781?
This trial is sponsored by Cedars-Sinai Medical Center, which has 360 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04564781 being conducted?
This trial has 5 study locations across California, Texas, Kyoto. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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