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NCT04556890 · ClinicalTrials.gov registry record · NA

Pain and Major Depressive Disorder

A NA study of Chronic Pain and Major Depressive Disorder, sponsored by University of California, Los Angeles.

Recruiting
Registry status
NA
Development phase
54
Enrollment target
1
Study location

NCT04556890: Recruiting NA study of Chronic Pain and Major Depressive Disorder, sponsored by University of California, Los Angeles.

NCT04556890 is a NA study of Chronic Pain and Major Depressive Disorder that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 54 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04556890, a NA study of Chronic Pain and Major Depressive Disorder, is actively recruiting participants, sponsored by University of California, Los Angeles.

RECRUITING
Registry status
NA
Development phase
54 participants
Enrollment target
1
Study location

Study Summary

This study will examine the effects of brain stimulation on pain symptoms associated with Major depressive disorder. This study will enroll 54 Subjects. Study subjects will be asked to complete surveys about their mood and well-being, 2 blood draws, 2 MRIs, 3 electroencephalograms, and receive 30 treatments of blinded transcranial magnetic stimulation. There is no control group as all subjects will receive some form of active treatment. Subjects are required to participate in 30-33 study visits and volunteer 40 hours of their time. Compensation for this study is $150 for completing all study activities.

Primary Outcome

Inventory of Depressive symptoms- Self (IDS-SR) scores will be analyzed as the primary outcome measure. The IDS-SR is a 30-item scale that measures various symptoms of depression. Each item is scored between 0-4. Severity of depression is associated with a higher score with scores ranging from 0 to 84.

Interventions

  • DEVICE Active rTMS/Active iTBS DFPLC/Sham Pain M1
  • DEVICE Active rTMS/Active iTBS

Study Locations (1)

California

  • UCLA Semel Institute - Los Angeles

Trial Details

FieldValue
Enrollment Target 54 participants
Start Date 2023-03-01
Est. Completion 2027-10-31
Phase NA

What NCT04556890 shows while recruiting

NCT04556890 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 54 participants, a relatively small participant target, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (93% lower).

The record links to 2 conditions, with Chronic Pain appearing as the primary indexed condition, and to 2 interventions - of which Active rTMS/Active iTBS DFPLC/Sham Pain M1 is the first listed.

NCT04556890 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT04556890 about?

NCT04556890 is a clinical study titled "Pain and Major Depressive Disorder". This study will examine the effects of brain stimulation on pain symptoms associated with Major depressive disorder. This study will enroll 54 Subjects. Study subjects will be asked to complete surveys about their mood and well-being, 2 blood draws, 2 MRIs, 3 electroencephalograms, and receive 30 tr...

What is the current status of trial NCT04556890?

This trial is currently recruiting. It is a NA study. The enrollment target is 54 participants. The study started on 2023-03-01. Estimated completion is 2027-10-31.

What conditions does trial NCT04556890 study?

This clinical trial studies the following conditions: Chronic Pain, Major Depressive Disorder.

What interventions are being tested in trial NCT04556890?

The interventions under investigation include: Active rTMS/Active iTBS DFPLC/Sham Pain M1 (DEVICE), Active rTMS/Active iTBS (DEVICE).

Who is sponsoring clinical trial NCT04556890?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04556890 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Chronic Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04556890's enrollment target sits among peer trials

54 193rd of 301 higher than 109 of 301 other Chronic Pain trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04556890, the US trial registry maintained by the National Library of Medicine. NCT04556890 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.