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NCT04553406 · ClinicalTrials.gov registry record · Phase 2

Safety, Tolerability, Pharmacokinetics and Efficacy of SPR720 for the Treatment of Patients With Mycobacterium Avium Complex (MAC) Pulmonary Disease

A Phase 2 study, sponsored by Spero Therapeutics.

Terminated
Registry status
Phase 2
Development phase
2
Enrollment target

NCT04553406 is a Phase 2 study that was terminated before completion, run by Spero Therapeutics. The registered enrollment target is 2 participants.

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The verdict

NCT04553406, a Phase 2 study, was terminated before completion, sponsored by Spero Therapeutics.

TERMINATED
Registry status
Phase 2
Development phase
2 participants
Enrollment target

Study Summary

To evaluate the pharmacokinetics (PK) of SPR719, the active moiety, generated from the orally (po) administered SPR720 prodrug in a patient population with nontuberculous mycobacteria pulmonary disease (NTM-PD)

Interventions

  • DRUG Placebo
  • DRUG SPR720
  • DRUG Open-label Standard of Care

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2020-12-03
Est. Completion 2021-01-28
Phase Phase 2

Sponsor

Spero Therapeutics

14 total trials

What the Registry Record Tells You About NCT04553406

The ClinicalTrials.gov registry entry for NCT04553406 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Spero Therapeutics, which has 14 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT04553406 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04553406 about?

NCT04553406 is a clinical study titled "Safety, Tolerability, Pharmacokinetics and Efficacy of SPR720 for the Treatment of Patients With Mycobacterium Avium Complex (MAC) Pulmonary Disease". To evaluate the pharmacokinetics (PK) of SPR719, the active moiety, generated from the orally (po) administered SPR720 prodrug in a patient population with nontuberculous mycobacteria pulmonary disease (NTM-PD)

What is the current status of trial NCT04553406?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 2 participants. The study started on 2020-12-03. Estimated completion is 2021-01-28.

What interventions are being tested in trial NCT04553406?

The interventions under investigation include: Placebo (DRUG), SPR720 (DRUG), Open-label Standard of Care (DRUG).

Who is sponsoring clinical trial NCT04553406?

This trial is sponsored by Spero Therapeutics, which has 14 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.