Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04426812 · ClinicalTrials.gov registry record
Measuring Chronic Pain Impact: Measurement Enhancement for Chronic Pain
A clinical trial of Chronic Pain, sponsored by RAND.
- Completed
- Registry status
- 11,146
- Enrollment target
- 1
- Study location
NCT04426812: Completed study of Chronic Pain, sponsored by RAND.
NCT04426812 is a study of Chronic Pain that has completed, run by RAND. The registered enrollment target is 11,146 participants, above the 735-participant average among 301 other Chronic Pain trials with a reported enrollment target (1416% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04426812, a study of Chronic Pain, has completed, sponsored by RAND.
- COMPLETED
- Registry status
- 11,146 participants
- Enrollment target
- 1
- Study location
Study Summary
Many complementary and integrative health approaches have been shown to be effective for chronic pain and included in guidelines. This evidence of effectiveness is built on hundreds of studies representing millions of research dollars, and the ability to analyze and better compare results across these studies is essential to obtain the full value of this investment. However, useful across-study comparisons which would allow better understanding and targeting of these interventions are hampered by at least two challenges: the lack of common outcome measures and the inability to meaningfully stratify or classify patients. The first two Aims of this study each address one of these two challenges. The last Aim takes advantage of this study to further test the viability of MTurk as a data collection platform. Specific Aim 1 addresses the lack of common outcome measures. This Aim is to develop and evaluate links or crosswalks between the PROMIS-29 and other common (legacy) measures used for chronic pain so that the results of studies using different measures can be compared. Our hypothesis here is that we will be able to create some sort of linkage between PROMIS and legacy measures that will allow for each pair estimates of one to be made from the other. Specific Aim 2 addresses the inability to meaningfully stratify or subclassify chronic pain patients. This Aim is to evaluate and refine the chronic pain impact stratification scheme (ISS) proposes by the NIH Research Task Force on chronic low back pain, which is based on 9 PROMIS-29 items. Our hypothesis here is that the ISS can be refined so that it can identify subgroups of chronic pain patients with different levels of morbidity and different needs for treatment. Specific Aim 3 addresses the potential for more efficient data collection using the MTurk platform. This Aim is to evaluate MTurk as a cost- and time-efficient method to collect quality data on individuals with chronic pain. Our hypothesis here is that w
Primary Outcome
Measure of function for those with chronic back pain; range 0-100; higher is worse
Conditions Studied
Interventions
- OTHER No intervention; just data collection
Study Locations (1)
California
- Online recruitment only - nationwide - Santa Monica
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11,146 participants |
| Start Date | 2021-08-30 |
| Est. Completion | 2024-11-25 |
What the finished NCT04426812 record still lists
NCT04426812 is an observational study that tracks outcomes without assigning an intervention. Its 11,146 participants enrollment target places it among the larger protocols in the corpus, above the 735-participant average among 301 other Chronic Pain trials with a reported enrollment target (1416% higher).
The record links to 1 condition, with Chronic Pain appearing as the primary indexed condition, and to 1 intervention - of which No intervention; just data collection is the first listed.
NCT04426812 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04426812 about?
NCT04426812 is a clinical study titled "Measuring Chronic Pain Impact: Measurement Enhancement for Chronic Pain". Many complementary and integrative health approaches have been shown to be effective for chronic pain and included in guidelines. This evidence of effectiveness is built on hundreds of studies representing millions of research dollars, and the ability to analyze and better compare results across the...
What is the current status of trial NCT04426812?
This trial is currently completed. The enrollment target is 11,146 participants. The study started on 2021-08-30. Estimated completion is 2024-11-25.
What conditions does trial NCT04426812 study?
This clinical trial studies the following conditions: Chronic Pain.
What interventions are being tested in trial NCT04426812?
The interventions under investigation include: No intervention; just data collection (OTHER).
Who is sponsoring clinical trial NCT04426812?
This trial is sponsored by RAND, which has 78 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04426812 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04426812's enrollment target sits among peer trials
11,146 5th of 301 higher than 297 of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Evaluating the Acceptability, Feasibility and Usability of Various Conversational Data Collection Software
RECRUITING · NA
-
Local Cerebral Oxygenation in Chronic Pain Patients Utilizing Spinal Cord Stimulation
RECRUITING · NA
-
Group Medical Visits and Chiropractic Care for Older Adults With Chronic Spine Pain
RECRUITING · NA
-
Emotional Awareness and Expression Therapy for People With Persistent Pain Following Orthopedic Trauma
RECRUITING · NA
-
Group-based Integrative Pain Management in Primary Care Safety Net Clinics
RECRUITING · NA
-
Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT06531824 · 11,000 participants · Phase 3
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
- NCT07136012 · 11,000 participants · Phase 3
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
- NCT07181109 · 11,000 participants · Phase 3
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
- NCT06677060 · 11,300 participants · Phase 3
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI