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COMPLETED Phase 3

A Study of the Efficacy and Safety of Relacorilant in Patients With Cortisol-Secreting Adrenal Adenomas

NCT04308590 · View on ClinicalTrials.gov ↗

Study Summary

This is a Phase 3, randomized, double-blind, placebo-controlled study to assess the efficacy, and safety of relacorilant to treat hypercortisolism in patients with cortisol-secreting adrenal adenoma or hyperplasia associated with diabetes mellitus/ impaired glucose tolerance (DM/IGT) and/or uncontrolled systolic hypertension (HTN).

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG Relacorilant

Study Locations (20)

Texas

  • Site 20 — Dallas
  • Site 03 — El Paso
  • Site 05 — Fort Worth

California

  • Site 17 — Stanford
  • Site 53 — Torrance

New York

  • Site 10 — Jamaica
  • Site 44 — New York

Ohio

  • Site 30 — Cleveland
  • Site 21 — Columbus

Alabama

  • Site 27 — Birmingham

Georgia

  • Site 07 — Atlanta

Indiana

  • Site 16 — Indianapolis

Louisiana

  • Site 09 — Metairie

Trial Details

FieldValue
Enrollment Target 137 participants
Start Date 2020-07-27
Est. Completion 2024-09-19
Phase Phase 3

Sponsor

Corcept Therapeutics

15 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04308590

The ClinicalTrials.gov registry entry for NCT04308590 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 137 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Corcept Therapeutics, which has 15 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hypercortisolism appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04308590 reports 20 study locations spanning 15 distinct geographic areas — top geographies include Texas, California, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04308590 about?

NCT04308590 is a clinical study titled "A Study of the Efficacy and Safety of Relacorilant in Patients With Cortisol-Secreting Adrenal Adenomas". This is a Phase 3, randomized, double-blind, placebo-controlled study to assess the efficacy, and safety of relacorilant to treat hypercortisolism in patients with cortisol-secreting adrenal adenoma or hyperplasia associated with diabetes mellitus/ impaired glucose tolerance (DM/IGT) and/or uncontro...

What is the current status of trial NCT04308590?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 137 participants. The study started on 2020-07-27. Estimated completion is 2024-09-19.

What conditions does trial NCT04308590 study?

This clinical trial studies the following conditions: Hypercortisolism. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04308590?

The interventions under investigation include: Placebo (OTHER), Relacorilant (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04308590?

This trial is sponsored by Corcept Therapeutics, which has 15 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04308590 being conducted?

This trial has 20 study locations across Alabama, California, Georgia, Indiana, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial