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NCT04217603 · ClinicalTrials.gov registry record · NA

Effect of CPAP on 6-Minute Walk Test Outcomes in Patients With ECAC

A NA study of Tracheobronchomalacia and Excessive Dynamic Airway Collapse, sponsored by Beth Israel Deaconess Medical Center.

Recruiting
Registry status
NA
Development phase
32
Enrollment target
1
Study location

NCT04217603 is a NA study of Tracheobronchomalacia and Excessive Dynamic Airway Collapse that is actively recruiting participants, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 32 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT04217603, a NA study of Tracheobronchomalacia and Excessive Dynamic Airway Collapse, is actively recruiting participants, sponsored by Beth Israel Deaconess Medical Center.

RECRUITING
Registry status
NA
Development phase
32 participants
Enrollment target
1
Study location

Study Summary

The purpose of this protocol is to perform a prospective, randomized, double-blinded, pacebo-controlled clinical trial to determine the influence of a non-invasive positive pressure ventilation device on exercise capacity and symptoms in adult patients with ECAC. Primary outcome will include the total distance traversed by the study subject during a standard 6-minute walk test, and secondary outcomes will include peak flow measurement and symptom reporting before and after the exercise testing. The study will focus on the use of continuous positive airway pressure (CPAP) device. CPAP is FDA-approved for the treatment of various medical conditions, including obstructive sleep apnea and heart failure, but is not FDA-approved for the treatment of ECAC. The study will enroll 32 ambulatory study subjects with confirmed ECAC at the BIDMC, and each study subject will be monitored for up to 3 months.

Interventions

  • DEVICE Continuous positive airway pressure (CPAP) device
  • DEVICE Sham-continuous positive airway pressure (CPAP) device

Study Locations (1)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2023-03-01
Est. Completion 2026-01-31
Phase NA

What the Registry Record Tells You About NCT04217603

The ClinicalTrials.gov registry entry for NCT04217603 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Tracheobronchomalacia appearing as the primary indexed condition, and to 2 interventions - of which Continuous positive airway pressure (CPAP) device is the first listed.

NCT04217603 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT04217603 about?

NCT04217603 is a clinical study titled "Effect of CPAP on 6-Minute Walk Test Outcomes in Patients With ECAC". The purpose of this protocol is to perform a prospective, randomized, double-blinded, pacebo-controlled clinical trial to determine the influence of a non-invasive positive pressure ventilation device on exercise capacity and symptoms in adult patients with ECAC. Primary outcome will include the tot...

What is the current status of trial NCT04217603?

This trial is currently recruiting. It is a NA study. The enrollment target is 32 participants. The study started on 2023-03-01. Estimated completion is 2026-01-31.

What conditions does trial NCT04217603 study?

This clinical trial studies the following conditions: Tracheobronchomalacia, Excessive Dynamic Airway Collapse.

What interventions are being tested in trial NCT04217603?

The interventions under investigation include: Continuous positive airway pressure (CPAP) device (DEVICE), Sham-continuous positive airway pressure (CPAP) device (DEVICE).

Who is sponsoring clinical trial NCT04217603?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04217603 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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