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NCT04134780 · ClinicalTrials.gov registry record
Ultrasound Imaging and Spectroscopy as Early Indicators of Locally-Advanced Breast Cancer Response
A clinical trial of Breast Cancer, sponsored by Sunnybrook Health Sciences Centre.
- Recruiting
- Registry status
- 150
- Enrollment target
- 3
- Study locations
NCT04134780: Recruiting study of Breast Cancer, sponsored by Sunnybrook Health Sciences Centre.
NCT04134780 is a study of Breast Cancer that is actively recruiting participants, run by Sunnybrook Health Sciences Centre. The registered enrollment target is 150 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (95% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04134780, a study of Breast Cancer, is actively recruiting participants, sponsored by Sunnybrook Health Sciences Centre.
- RECRUITING
- Registry status
- 150 participants
- Enrollment target
- 3
- Study locations
Study Summary
This work explores the possibility of using ultrasound imaging and spectroscopy as a way of monitoring cell death, hence, tumour response to treatment. The hypothesis here is that it can be used as a way of monitoring early response to cancer treatment and predicting which patients continue on in their therapy to have a complete pathological response as a primary endpoint and tumour size decrease as a secondary endpoint. If this work is successful it could be used in the future early on in a cancer patient's treatment to predict whether or not a course of chemotherapy or radiotherapy is going to be successful. For example, in patients in which the analysis indicates a poor response the chemotherapy regimen could be changed to a more efficacious one or for those receiving radiotherapy predicted to have a poor response a radiosensitizing agent could be used to improve outcome.
Primary Outcome
Correlate changes in ultrasound backscatter parameters obtained throughout the course of treatment with pathological complete or partial response
Conditions Studied
Study Locations (3)
Ontario
- Sunnybrook Health Sciences Centre - Toronto
- Princess Margaret Cancer Centre - Toronto
Texas
- MD Anderson - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2014-08 |
| Est. Completion | 2029-10 |
What NCT04134780 shows while recruiting
NCT04134780 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 0 interventions.
NCT04134780 reports a single indexed study location in Ontario, Texas.
Frequently Asked Questions
What is clinical trial NCT04134780 about?
NCT04134780 is a clinical study titled "Ultrasound Imaging and Spectroscopy as Early Indicators of Locally-Advanced Breast Cancer Response". This work explores the possibility of using ultrasound imaging and spectroscopy as a way of monitoring cell death, hence, tumour response to treatment. The hypothesis here is that it can be used as a way of monitoring early response to cancer treatment and predicting which patients continue on in th...
What is the current status of trial NCT04134780?
This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2014-08. Estimated completion is 2029-10.
What conditions does trial NCT04134780 study?
This clinical trial studies the following conditions: Breast Cancer.
Who is sponsoring clinical trial NCT04134780?
This trial is sponsored by Sunnybrook Health Sciences Centre, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04134780 being conducted?
This trial has 3 study locations across Texas, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04134780's enrollment target sits among peer trials
150 444th of 1224 higher than 772 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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