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NCT04027387 · ClinicalTrials.gov registry record · Phase 1

Dose Escalation Safety Study of TMB-365 in HIV-1 Infected Participants

A Phase 1 study, sponsored by TaiMed Biologics.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target

NCT04027387 is a Phase 1 study that has completed, run by TaiMed Biologics. The registered enrollment target is 24 participants.

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The verdict

NCT04027387, a Phase 1 study, has completed, sponsored by TaiMed Biologics.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target

Study Summary

This study will evaluate the safety and behavior in the body of the experimental drug TMB-365 in people with HIV-1 infection. This will be the first test of TMB-365 in humans. One dose of the study drug is given to each participant, followed by 10 weeks of monitoring for safety and levels of the drug in the blood. The first group of participants will receive the lowest dose (400 mg). If no safety concerns are seen, the next group will begin at a higher dose (800 mg). If no safety concerns are seen in the second group, the third group will begin at the highest dose in this study (1600 mg).

Interventions

  • BIOLOGICAL TMB-365

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2019-12-14
Est. Completion 2021-08-18
Phase Phase 1

Sponsor

TaiMed Biologics

9 total trials

What the Registry Record Tells You About NCT04027387

The ClinicalTrials.gov registry entry for NCT04027387 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is TaiMed Biologics, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which TMB-365 is the first listed.

NCT04027387 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04027387 about?

NCT04027387 is a clinical study titled "Dose Escalation Safety Study of TMB-365 in HIV-1 Infected Participants". This study will evaluate the safety and behavior in the body of the experimental drug TMB-365 in people with HIV-1 infection. This will be the first test of TMB-365 in humans. One dose of the study drug is given to each participant, followed by 10 weeks of monitoring for safety and levels of the dru...

What is the current status of trial NCT04027387?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2019-12-14. Estimated completion is 2021-08-18.

What interventions are being tested in trial NCT04027387?

The interventions under investigation include: TMB-365 (BIOLOGICAL).

Who is sponsoring clinical trial NCT04027387?

This trial is sponsored by TaiMed Biologics, which has 9 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.