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NCT03787498 · ClinicalTrials.gov registry record · Phase 1

A Study of PLX2853 in Relapsed or Refractory Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

A Phase 1 study of Relapsed Acute Myeloid Leukemia (AML) and Refractory Acute Myeloid Leukemia (AML), sponsored by Opna Bio.

Completed
Registry status
Phase 1
Development phase
22
Enrollment target
6
Study locations

NCT03787498 is a Phase 1 study of Relapsed Acute Myeloid Leukemia (AML) and Refractory Acute Myeloid Leukemia (AML) that has completed, run by Opna Bio. The registered enrollment target is 22 participants. The trial reports 6 study locations across 6 states.

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The verdict

NCT03787498, a Phase 1 study of Relapsed Acute Myeloid Leukemia (AML) and Refractory Acute Myeloid Leukemia (AML), has completed, sponsored by Opna Bio.

COMPLETED
Registry status
Phase 1
Development phase
22 participants
Enrollment target
6
Study locations

Study Summary

The purpose of this research study is to evaluate safety, pharmacokinetics, pharmacodynamics and preliminary efficacy of the investigational drug PLX2853 in subjects with Relapsed or Refractory Acute Myeloid Leukemia or High-risk Myelodysplastic Syndrome

Interventions

  • DRUG PLX2853

Study Locations (6)

Georgia

  • Northside Hospital - Atlanta

Maryland

  • Sidney Kimmel Comprehensive Cancer At Johns Hopkins - Baltimore

New York

  • NewYork-Presbyterian / Weill Cornell Medical Center - New York

Ohio

  • Ohio State University Medical Center - Columbus

Oregon

  • Oregon Health and Sciences University - Portland

Texas

  • University of Texas MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2019-03-19
Est. Completion 2021-06-30
Phase Phase 1

Sponsor

Opna Bio

5 total trials

What the Registry Record Tells You About NCT03787498

The ClinicalTrials.gov registry entry for NCT03787498 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Opna Bio, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Relapsed Acute Myeloid Leukemia (AML) appearing as the primary indexed condition, and to 1 intervention - of which PLX2853 is the first listed.

NCT03787498 reports 6 study locations spanning 6 distinct geographic areas - top geographies include Georgia, Maryland, New York.

Frequently Asked Questions

What is clinical trial NCT03787498 about?

NCT03787498 is a clinical study titled "A Study of PLX2853 in Relapsed or Refractory Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome". The purpose of this research study is to evaluate safety, pharmacokinetics, pharmacodynamics and preliminary efficacy of the investigational drug PLX2853 in subjects with Relapsed or Refractory Acute Myeloid Leukemia or High-risk Myelodysplastic Syndrome

What is the current status of trial NCT03787498?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2019-03-19. Estimated completion is 2021-06-30.

What conditions does trial NCT03787498 study?

This clinical trial studies the following conditions: Relapsed Acute Myeloid Leukemia (AML), Refractory Acute Myeloid Leukemia (AML), High-risk Myelodysplastic Syndrome (MDS).

What interventions are being tested in trial NCT03787498?

The interventions under investigation include: PLX2853 (DRUG).

Who is sponsoring clinical trial NCT03787498?

This trial is sponsored by Opna Bio, which has 5 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03787498 being conducted?

This trial has 6 study locations across Georgia, Maryland, New York, Ohio, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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