Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03729817 · ClinicalTrials.gov registry record · NA
REstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis
A NA study, sponsored by Case Western Reserve University.
- Not yet
- Registry status
- NA
- Development phase
- 159
- Enrollment target
NCT03729817: Clinical Trial NA study, sponsored by Case Western Reserve University.
NCT03729817 is a NA study that has not yet begun recruiting, run by Case Western Reserve University. The registered enrollment target is 159 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03729817, a NA study, has not yet begun recruiting, sponsored by Case Western Reserve University.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 159 participants
- Enrollment target
Study Summary
By assessing the safety and durability of an endovascular intervention, this study will justify and inform the design of a subsequent seamless feasibility/pivotal trial aimed at the treatment of intracranial atherosclerotic stenosis (ICAS), an entity which carries a high risk of stroke despite existing medical therapies, and has no other treatment options. Given the global burden of ICAS as a leading cause of stroke, there is a high potential for public health impact not just in the U.S., but world-wide.
Primary Outcome
Any stroke (ischemic or hemorrhagic), or death, within 30 days following submaximal angioplasty
Interventions
- DEVICE Submaximal balloon angioplasty
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 159 participants |
| Start Date | 2027-10 |
| Est. Completion | 2032-10-31 |
| Phase | NA |
What is known before NCT03729817 opens enrollment
NCT03729817 is an interventional study that assigns participants to a tested intervention. The registered 159 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 1 intervention - of which Submaximal balloon angioplasty is the first listed.
NCT03729817 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03729817 about?
NCT03729817 is a clinical study titled "REstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis". By assessing the safety and durability of an endovascular intervention, this study will justify and inform the design of a subsequent seamless feasibility/pivotal trial aimed at the treatment of intracranial atherosclerotic stenosis (ICAS), an entity which carries a high risk of stroke despite exist...
What is the current status of trial NCT03729817?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 159 participants. The study started on 2027-10. Estimated completion is 2032-10-31.
What interventions are being tested in trial NCT03729817?
The interventions under investigation include: Submaximal balloon angioplasty (DEVICE).
Who is sponsoring clinical trial NCT03729817?
This trial is sponsored by Case Western Reserve University, which has 141 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03729817's enrollment target sits among peer trials
159 654th of 2000 higher than 1,347 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT05267626 · 159 participants · Phase 1
Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
- NCT06321575 · 159 participants · NA
The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)
- NCT06729151 · 159 participants
Effect of Intradetrusor onabotulinumtoxinA Injection Versus Conservative Management on Female Sexual Function in Patients With Bladder Pain Syndrome
- NCT07023731 · 159 participants · Phase 1
A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia