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NCT03687632 · ClinicalTrials.gov registry record · Phase 2

ST266 Eye Drops for the Treatment of Persistent Corneal Epithelial Defects

A Phase 2 study, sponsored by Noveome Biotherapeutics, formerly Stemnion.

Completed
Registry status
Phase 2
Development phase
13
Enrollment target

NCT03687632: Completed Phase 2 study, sponsored by Noveome Biotherapeutics, formerly Stemnion.

NCT03687632 is a Phase 2 study that has completed, run by Noveome Biotherapeutics, formerly Stemnion. The registered enrollment target is 13 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03687632, a Phase 2 study, has completed, sponsored by Noveome Biotherapeutics, formerly Stemnion.

COMPLETED
Registry status
Phase 2
Development phase
13 participants
Enrollment target

Study Summary

The primary aim of the study is to evaluate the clinical response of ST266 treated subjects with persistent corneal epithelial defects during 28 days of therapy. The secondary endpoint is the response rate within 14 days of treatment.

Primary Outcome

Healing is defined as the complete re-epithelialization of the epithelial defect as determined by slit lamp examination with fluorescein staining.

Interventions

  • BIOLOGICAL ST266

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2019-06-10
Est. Completion 2020-08-25
Phase Phase 2

What the finished NCT03687632 record still lists

NCT03687632 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 1 intervention - of which ST266 is the first listed.

NCT03687632 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03687632 about?

NCT03687632 is a clinical study titled "ST266 Eye Drops for the Treatment of Persistent Corneal Epithelial Defects". The primary aim of the study is to evaluate the clinical response of ST266 treated subjects with persistent corneal epithelial defects during 28 days of therapy. The secondary endpoint is the response rate within 14 days of treatment.

What is the current status of trial NCT03687632?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 13 participants. The study started on 2019-06-10. Estimated completion is 2020-08-25.

What interventions are being tested in trial NCT03687632?

The interventions under investigation include: ST266 (BIOLOGICAL).

Who is sponsoring clinical trial NCT03687632?

This trial is sponsored by Noveome Biotherapeutics, formerly Stemnion, which has 12 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03687632's enrollment target sits among peer trials

13 1947th of 2000 higher than 53 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03687632, the US trial registry maintained by the National Library of Medicine. NCT03687632 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.