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NCT03677206 · ClinicalTrials.gov registry record · NA
The Effect of Light Therapy on Chronic Pain
A NA study of Chronic Pain, sponsored by University of Arizona.
- Active
- Registry status
- NA
- Development phase
- 55
- Enrollment target
- 1
- Study location
NCT03677206: Active NA study of Chronic Pain, sponsored by University of Arizona.
NCT03677206 is a NA study of Chronic Pain that is active but no longer recruiting, run by University of Arizona. The registered enrollment target is 55 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03677206, a NA study of Chronic Pain, is active but no longer recruiting, sponsored by University of Arizona.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 55 participants
- Enrollment target
- 1
- Study location
Study Summary
Chronic pain is a major problem in the USA and the rest of the world, currently, all available pharmacological interventions carry with them significant side effects. Pain clinics are specially equipped to perform intentional pain procedures to manage pain. However, there remain groups of patients what neither benefit from pharmacological nor from interventional pain procedures. Other methods have shown only minor benefits such as hypnosis or cognitive behavioral therapy. Therefore, other techniques need to be investigated. Light therapy has been shown to have significant biological effects on humans. For example, light therapy is used to manage depression. Several clinical trials have shown that certain wavelengths of light can improve wound healing, decrease temporomandibular joint dysfunction (TMJ) pain, and decrease fear of back pain. In these trials, light was directed at the site of pain. In an attempt to better understand the effect of different wavelengths of light, pre-clinical studies were conducted using rats. The investigators have shown green and blue Light emitting diode, (LED) light produced antinociception (analgesia) and reversed neuropathic pain associated with several models of chronic pain. The analgesic effect of light was completely blocked when rats had their eyes covered, this suggests that the analgesic effects seen are mainly due to systemic effect through the visual system. Preliminary experiments on rats suggest that this effect is mediated through the endogenous opioids and cannabinoid system. The investigators believe that LED light is a safe alternative to pharmacological intervention to manage pain by stimulating the endogenous endorphin and cannabinoid systems. The investigators initial target participants with history of HIV, chemotherapy induced peripheral neuropathy and fibromyalgia. Participants will be divided into 2 groups. The first group will be a control group exposed to white LED light. The second group will be exposed t
Primary Outcome
Change in the intensity of chronic pain as measured by the Numerical Pain Scale (NPS). The NPS has a value ranging from 0 to 10 out of a maximum of 10. 0 means no pain. 10 means the most severe pain.
Conditions Studied
Interventions
- DEVICE Exposure to green LED light
- DEVICE Exposure to white LED light
Study Locations (1)
Arizona
- Banner University Medical Center South - Tucson
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2016-06 |
| Est. Completion | 2026-12 |
| Phase | NA |
What the registry record for NCT03677206 still lists
NCT03677206 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 55 participants, a relatively small participant target, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Chronic Pain appearing as the primary indexed condition, and to 2 interventions - of which Exposure to green LED light is the first listed.
NCT03677206 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT03677206 about?
NCT03677206 is a clinical study titled "The Effect of Light Therapy on Chronic Pain". Chronic pain is a major problem in the USA and the rest of the world, currently, all available pharmacological interventions carry with them significant side effects. Pain clinics are specially equipped to perform intentional pain procedures to manage pain. However, there remain groups of patients w...
What is the current status of trial NCT03677206?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 55 participants. The study started on 2016-06. Estimated completion is 2026-12.
What conditions does trial NCT03677206 study?
This clinical trial studies the following conditions: Chronic Pain.
What interventions are being tested in trial NCT03677206?
The interventions under investigation include: Exposure to green LED light (DEVICE), Exposure to white LED light (DEVICE).
Who is sponsoring clinical trial NCT03677206?
This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03677206 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03677206's enrollment target sits among peer trials
55 192nd of 301 higher than 110 of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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