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NCT03579953 · ClinicalTrials.gov registry record · Early Phase 1
Nicotine TMS EFT Smoking Pilot Study
A Early Phase 1 study, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 16
- Enrollment target
NCT03579953: Completed Early Phase 1 study, sponsored by Medical University of South Carolina.
NCT03579953 is a Early Phase 1 study that has completed, run by Medical University of South Carolina. The registered enrollment target is 16 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03579953, a Early Phase 1 study, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
Prior and recent evidence suggests a role of medial prefrontal cortex (MPFC) in cigarette smoking. Episodic Future Thinking (EFT) has also been shown to be associated with increased delayed discounting and reduced cigarette self administration. In the present study, we will examine whether a single administration of theta-burst transcranial magnetic stimulation (tbTMS) can increase Episodic Future Thinking and delayed discounting while reducing craving for nicotine.
Primary Outcome
The effect of real versus sham cTBS on nicotine craving will be assessed by comparing pre-TMS and post-TMS changes in nicotine craving scores.
Interventions
- DEVICE Sham cTBS
- DEVICE Real cTBS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2018-05-22 |
| Est. Completion | 2019-06-10 |
| Phase | Early Phase 1 |
What the finished NCT03579953 record still lists
NCT03579953 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 2 interventions - of which Sham cTBS is the first listed.
NCT03579953 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03579953 about?
NCT03579953 is a clinical study titled "Nicotine TMS EFT Smoking Pilot Study". Prior and recent evidence suggests a role of medial prefrontal cortex (MPFC) in cigarette smoking. Episodic Future Thinking (EFT) has also been shown to be associated with increased delayed discounting and reduced cigarette self administration. In the present study, we will examine whether a single ...
What is the current status of trial NCT03579953?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 16 participants. The study started on 2018-05-22. Estimated completion is 2019-06-10.
What interventions are being tested in trial NCT03579953?
The interventions under investigation include: Sham cTBS (DEVICE), Real cTBS (DEVICE).
Who is sponsoring clinical trial NCT03579953?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03579953's enrollment target sits among peer trials
16 1370th of 2000 higher than 598 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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