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NCT03554928 · ClinicalTrials.gov registry record

Longitudinal Assessment of Functional Connectivity in Treatment Engaged Cocaine Users

A clinical trial, sponsored by Medical University of South Carolina.

Completed
Registry status
24
Enrollment target

NCT03554928 is a clinical trial that has completed, run by Medical University of South Carolina. The registered enrollment target is 24 participants.

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The verdict

NCT03554928 has completed, sponsored by Medical University of South Carolina.

COMPLETED
Registry status
24 participants
Enrollment target

Study Summary

High-relapse rates to addiction are likely due to motivational (limbic) and cognitive (executive) factors. The purpose of this proposal is to determine the relationship between functional connectivity in executive control regions (namely the dorsolateral prefrontal cortex) and both proximal and extended outcomes in treatment seeking cocaine and opiate users. This longitudinal neuroimaging study will assess the integrity of executive and limbic circuits 4 timepoints before and after a 28-day intensive outpatient treatment program. Controls will also be recruited as a comparison group. The fundamental neuroscience knowledge gained from this proposal will be used to develop new evidence-based brain stimulation treatment strategies to enhance the integrity of these circuits and subsequent outcomes in traditional treatment programs. The purpose of this study is not only to look at the integrity of these circuits in individuals entering treatment but also to see how these circuits change after treatment and if this can be used to predict outcomes. From the larger societal perspective this research may help us determine which individuals are likely going to benefit the most from treatment and perhaps those that are at a greater risk for relapse.

Interventions

  • DIAGNOSTIC_TEST magnetic resonance imaging

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2015-08-01
Est. Completion 2019-06-09

What the Registry Record Tells You About NCT03554928

The ClinicalTrials.gov registry entry for NCT03554928 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which magnetic resonance imaging is the first listed.

NCT03554928 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03554928 about?

NCT03554928 is a clinical study titled "Longitudinal Assessment of Functional Connectivity in Treatment Engaged Cocaine Users". High-relapse rates to addiction are likely due to motivational (limbic) and cognitive (executive) factors. The purpose of this proposal is to determine the relationship between functional connectivity in executive control regions (namely the dorsolateral prefrontal cortex) and both proximal and exte...

What is the current status of trial NCT03554928?

This trial is currently completed. The enrollment target is 24 participants. The study started on 2015-08-01. Estimated completion is 2019-06-09.

What interventions are being tested in trial NCT03554928?

The interventions under investigation include: magnetic resonance imaging (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT03554928?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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