Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03347955 · ClinicalTrials.gov registry record · NA
Double-blind Placebo Surgery Trial for Treatment of Parkinson's Disease
A NA study, sponsored by University of Denver.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT03347955: Completed NA study, sponsored by University of Denver.
NCT03347955 is a NA study that has completed, run by University of Denver. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03347955, a NA study, has completed, sponsored by University of Denver.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
A double-blind sham surgery-controlled trial was developed to determine the effectiveness of implantation of human embryonic dopamine neurons into the putamen of patients with advanced Parkinson's disease (PD), with half the patients receiving the implant (n = 20) and half receiving sham surgery (n = 20). The blind was maintained for 12 months before participants were told which surgery they received, at which time those receiving sham surgery could request the implant surgery.
Primary Outcome
one item scale where participants marked their answer on a scale ranging from -3 (much worse since surgery) to 0 (no change) to +3 (much improved since surgery)
Interventions
- PROCEDURE Sham surgery
- PROCEDURE Neural implantation group
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 1994-11 |
| Est. Completion | 1999-02 |
| Phase | NA |
What the finished NCT03347955 record still lists
NCT03347955 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Sham surgery is the first listed.
NCT03347955 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03347955 about?
NCT03347955 is a clinical study titled "Double-blind Placebo Surgery Trial for Treatment of Parkinson's Disease". A double-blind sham surgery-controlled trial was developed to determine the effectiveness of implantation of human embryonic dopamine neurons into the putamen of patients with advanced Parkinson's disease (PD), with half the patients receiving the implant (n = 20) and half receiving sham surgery (n ...
What is the current status of trial NCT03347955?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 1994-11. Estimated completion is 1999-02.
What interventions are being tested in trial NCT03347955?
The interventions under investigation include: Sham surgery (PROCEDURE), Neural implantation group (PROCEDURE).
Who is sponsoring clinical trial NCT03347955?
This trial is sponsored by University of Denver, which has 13 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03347955's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01306019 · 40 participants · Phase 1
Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
- NCT01608152 · 40 participants
Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors
- NCT01668082 · 40 participants · NA
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection
- NCT02015013 · 40 participants · Phase 2
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia