Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03331302 · ClinicalTrials.gov registry record · Phase 1
Hyper Polarized Xenon-129 MRI vs Xenon-133 Scintigraphy
A Phase 1 study of Chronic Obstructive Pulmonary Disease, sponsored by University of Virginia.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT03331302: Recruiting Phase 1 study of Chronic Obstructive Pulmonary Disease, sponsored by University of Virginia.
NCT03331302 is a Phase 1 study of Chronic Obstructive Pulmonary Disease that is actively recruiting participants, run by University of Virginia. The registered enrollment target is 30 participants, below the 1,754-participant average among 86 other Chronic Obstructive Pulmonary Disease trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03331302, a Phase 1 study of Chronic Obstructive Pulmonary Disease, is actively recruiting participants, sponsored by University of Virginia.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Hyper polarized Xenon-129 MRI will be directly compared to a radioactive Xe-133 scintigraphy to detect defects in lung ventilation from airflow limitation. This study is conducted as a pilot study with intention to conduct a larger clinical trial.
Primary Outcome
Compare the quality of the imaging between hyper polarized xenon-129 and radioactive xenon-133
Conditions Studied
Interventions
- DRUG Hyperpolarized Xenon-129 MRI (Experimental)
- DRUG Radioactive Xenon-133 scintigraphy (Active Comparator)
Study Locations (1)
Virginia
- University of Virginia Health System - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2018-09-01 |
| Est. Completion | 2020-12-31 |
| Phase | Phase 1 |
What NCT03331302 shows while recruiting
NCT03331302 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,754-participant average among 86 other Chronic Obstructive Pulmonary Disease trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Chronic Obstructive Pulmonary Disease appearing as the primary indexed condition, and to 2 interventions - of which Hyperpolarized Xenon-129 MRI (Experimental) is the first listed.
NCT03331302 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT03331302 about?
NCT03331302 is a clinical study titled "Hyper Polarized Xenon-129 MRI vs Xenon-133 Scintigraphy". Hyper polarized Xenon-129 MRI will be directly compared to a radioactive Xe-133 scintigraphy to detect defects in lung ventilation from airflow limitation. This study is conducted as a pilot study with intention to conduct a larger clinical trial.
What is the current status of trial NCT03331302?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2018-09-01. Estimated completion is 2020-12-31.
What conditions does trial NCT03331302 study?
This clinical trial studies the following conditions: Chronic Obstructive Pulmonary Disease.
What interventions are being tested in trial NCT03331302?
The interventions under investigation include: Hyperpolarized Xenon-129 MRI (Experimental) (DRUG), Radioactive Xenon-133 scintigraphy (Active Comparator) (DRUG).
Who is sponsoring clinical trial NCT03331302?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03331302 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Obstructive Pulmonary Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03331302's enrollment target sits among peer trials
30 67th of 86 higher than 16 of 86 other Chronic Obstructive Pulmonary Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Obstructive Pulmonary Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Feasibility of Semaglutide in Advanced Lung Disease
RECRUITING · Phase 1
-
A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease
RECRUITING · Phase 1
-
: Vascular Function in Health and Disease
RECRUITING · Phase 1
-
Safety and Efficacy of Adipose Derived Stem Cells for Chronic Obstructive Pulmonary Disease
COMPLETED · Phase 1
-
Safety, Tolerability, and Pharmacokinetics of Andecaliximab in Adults With Chronic Obstructive Pulmonary Disease (COPD)
COMPLETED · Phase 1
-
Mindfulness Based Stress Reduction in COPD
COMPLETED · Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00977977 · 30 participants · Phase 2
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
- NCT01459107 · 30 participants · Phase 2
Human Upper Extremity Allotransplantation
- NCT01666080 · 30 participants · NA
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)
- NCT01720836 · 30 participants · Phase 1
Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI