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NCT03211520 · ClinicalTrials.gov registry record
Magnetic Resonance Imaging:A Window to Anthracycline Toxicity
A clinical trial of Cardiac Complications, sponsored by Connecticut Children's Medical Center.
- Completed
- Registry status
- 13
- Enrollment target
- 1
- Study location
NCT03211520: Completed study of Cardiac Complications, sponsored by Connecticut Children's Medical Center.
NCT03211520 is a study of Cardiac Complications that has completed, run by Connecticut Children's Medical Center. The registered enrollment target is 13 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03211520, a study of Cardiac Complications, has completed, sponsored by Connecticut Children's Medical Center.
- COMPLETED
- Registry status
- 13 participants
- Enrollment target
- 1
- Study location
Study Summary
The study is being conducted to see which cardiac tests that monitor how the heart functions during and after treatment with anthracyclines are most effective. This study will assess a new way to check the heart function of children during and after cancer treatment. Currently, doctors use echocardiograms (heart ultrasound) to see how the heart is working. Echocardiograms are currently being done as part of standard of care prior to giving anthracycline chemotherapy doses and if any cardiac problems are suspected. The new method involves Cardiac Magnetic Resonance Imagining (CMRI) and a blood tests for certain biomarkers for heart health: High sensitivity troponin, Caspase, C-reactive Protein (CRP), ventricular derived B-type natriuretic peptide (BNP), Matrix Metalloproteinases (MMPs), Tissue inhibitors of metalloproteinases (TIMPs), C terminal propeptide of type I procollagen (PICP), C terminal telopeptide of collagen type I (CITP), Troponin I, and Bone Alkaline Phosphatase. The purpose of this study is to find out if CMRI and blood tests help us to find heart problems earlier, before they are detected by echocardiograms.
Primary Outcome
Myocardial edema in the acute phase measured by a composite of multiple measures that include T1 and T2 mapping, signal enhancement in T2 weighted images.
Conditions Studied
Study Locations (1)
Connecticut
- Olga H Toro-Salazar - Hartford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2013-02 |
| Est. Completion | 2023-06-24 |
What the finished NCT03211520 record still lists
NCT03211520 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 13 participants, a relatively small participant target.
The record links to 1 condition, with Cardiac Complications appearing as the primary indexed condition, and to 0 interventions.
NCT03211520 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT03211520 about?
NCT03211520 is a clinical study titled "Magnetic Resonance Imaging:A Window to Anthracycline Toxicity". The study is being conducted to see which cardiac tests that monitor how the heart functions during and after treatment with anthracyclines are most effective. This study will assess a new way to check the heart function of children during and after cancer treatment. Currently, doctors use echocardi...
What is the current status of trial NCT03211520?
This trial is currently completed. The enrollment target is 13 participants. The study started on 2013-02. Estimated completion is 2023-06-24.
What conditions does trial NCT03211520 study?
This clinical trial studies the following conditions: Cardiac Complications.
Who is sponsoring clinical trial NCT03211520?
This trial is sponsored by Connecticut Children's Medical Center, which has 55 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03211520 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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