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NCT03203174 · ClinicalTrials.gov registry record · Phase 1
The Use of Microneedles With Topical Botulinum Toxin for Treatment of Palmar Hyperhidrosis
A Phase 1 study, sponsored by University of California, Davis.
- Completed
- Registry status
- Phase 1
- Development phase
- 13
- Enrollment target
NCT03203174: Completed Phase 1 study, sponsored by University of California, Davis.
NCT03203174 is a Phase 1 study that has completed, run by University of California, Davis. The registered enrollment target is 13 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03203174, a Phase 1 study, has completed, sponsored by University of California, Davis.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 13 participants
- Enrollment target
Study Summary
Hyperhidrosis or sweating of palms results from the overactivity of sweat glands and leads to psychosocial impairment with reduction in quality of life in those that are affected. Injection of botulinum toxin has been shown to be effective in reducing the symptoms of hyperhidrosis with associated improvement in quality of life, but is usually very painful. Microneedles are a different modality for transdermal drug penetration without the pain. This study aims to understand if botulinum toxin A can be delivered topically after microneedle pretreatment in hopes of developing a minimally painful treatment protocol for treatment of palmar hyperhidrosis.
Primary Outcome
a scale from 1 to 4. Values of 1 or 2 represent Mild/moderate disease, and 3 or 4 represent severe disease.
Interventions
- OTHER Saline
- DRUG Botulinum Toxin Type A
- DEVICE Microneedle
- DEVICE Sham Microneedle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2015-01 |
| Est. Completion | 2016-08-02 |
| Phase | Phase 1 |
What the finished NCT03203174 record still lists
NCT03203174 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (78% lower).
The record links to 0 conditions, and to 4 interventions - of which Saline is the first listed.
NCT03203174 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03203174 about?
NCT03203174 is a clinical study titled "The Use of Microneedles With Topical Botulinum Toxin for Treatment of Palmar Hyperhidrosis". Hyperhidrosis or sweating of palms results from the overactivity of sweat glands and leads to psychosocial impairment with reduction in quality of life in those that are affected. Injection of botulinum toxin has been shown to be effective in reducing the symptoms of hyperhidrosis with associated im...
What is the current status of trial NCT03203174?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 13 participants. The study started on 2015-01. Estimated completion is 2016-08-02.
What interventions are being tested in trial NCT03203174?
The interventions under investigation include: Saline (OTHER), Botulinum Toxin Type A (DRUG), Microneedle (DEVICE), Sham Microneedle (DEVICE).
Who is sponsoring clinical trial NCT03203174?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03203174's enrollment target sits among peer trials
13 1847th of 2000 higher than 149 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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