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NCT03137069 · ClinicalTrials.gov registry record · Phase 2

A Study of GDC-0853 in Participants With Refractory Chronic Spontaneous Urticaria (CSU).

A Phase 2 study of Urticaria, sponsored by Genentech.

Completed
Registry status
Phase 2
Development phase
134
Enrollment target
20
Study locations

NCT03137069 is a Phase 2 study of Urticaria that has completed, run by Genentech. The registered enrollment target is 134 participants, above the 16-participant average among 3 other Urticaria trials with a reported enrollment target (738% higher). The trial reports 20 study locations across 11 states.

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The verdict

NCT03137069, a Phase 2 study of Urticaria, has completed, sponsored by Genentech.

COMPLETED
Registry status
Phase 2
Development phase
134 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to evaluate the efficacy, safety and pharmacokinetics of GDC-0853 compared with placebo in participants with Refractory Chronic Spontaneous Urticaria (CSU) already treated with anti-histamines. Participants have the option to enter the Open-Label Extension (OLE) study after completing the 8-week treatment period.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG GDC-0853

Study Locations (20)

California

  • Kern Allergy Med Clinic, Inc. - Bakersfield
  • Southern California Research Center - Mission Viejo
  • Allergy & Asthma Consultants - Redwood City
  • Integrated Research Group Inc - Riverside
  • Integrated Research of Inland - Upland

Ontario

  • Private Practice - Dr. Jason Ohayon - Hamilton
  • Lynde Institute for Dermatology - Markham
  • Cheema Research - Mississauga
  • Yang Medicine - Ottawa
  • Gordon Sussman Clinical Research - Toronto

Florida

  • New Horizon Research Center - Miami
  • Renstar Medical Research - Ocala

Alabama

  • Clinical Research Center of Alabama, LLC - Birmingham

Arizona

  • Allergy & Asthma Immunology Associates - Scottsdale

Oklahoma

  • Vital Prospects Clinical Research Institute PC - CRN - Tulsa

Rhode Island

  • Asthma, Nasal Disease, and Allergy Research Center of New England - East Providence

Texas

  • Center for Clinical Studies - Cypress

Trial Details

FieldValue
Enrollment Target 134 participants
Start Date 2017-05-26
Est. Completion 2019-10-25
Phase Phase 2

Sponsor

Genentech

332 total trials

What the Registry Record Tells You About NCT03137069

The ClinicalTrials.gov registry entry for NCT03137069 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 134 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 16-participant average among 3 other Urticaria trials with a reported enrollment target (738% higher). The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Urticaria appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT03137069 reports 20 study locations spanning 11 distinct geographic areas - top geographies include California, Ontario, Florida.

Frequently Asked Questions

What is clinical trial NCT03137069 about?

NCT03137069 is a clinical study titled "A Study of GDC-0853 in Participants With Refractory Chronic Spontaneous Urticaria (CSU).". The purpose of this study is to evaluate the efficacy, safety and pharmacokinetics of GDC-0853 compared with placebo in participants with Refractory Chronic Spontaneous Urticaria (CSU) already treated with anti-histamines. Participants have the option to enter the Open-Label Extension (OLE) study af...

What is the current status of trial NCT03137069?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 134 participants. The study started on 2017-05-26. Estimated completion is 2019-10-25.

What conditions does trial NCT03137069 study?

This clinical trial studies the following conditions: Urticaria.

What interventions are being tested in trial NCT03137069?

The interventions under investigation include: Placebo (DRUG), GDC-0853 (DRUG).

Who is sponsoring clinical trial NCT03137069?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03137069 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Florida, Oklahoma. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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