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NCT03117166 · ClinicalTrials.gov registry record · Phase 1

Effect of Intravenous Lidocaine, Used to Attenuate Pain With Propofol Injection, on Defibrillation Threshold Testing

A Phase 1 study, sponsored by Drexel University College of Medicine.

Terminated
Registry status
Phase 1
Development phase
19
Enrollment target

NCT03117166: Clinical Trial Phase 1 study, sponsored by Drexel University College of Medicine.

NCT03117166 is a Phase 1 study that was terminated before completion, run by Drexel University College of Medicine. The registered enrollment target is 19 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03117166, a Phase 1 study, was terminated before completion, sponsored by Drexel University College of Medicine.

TERMINATED
Registry status
Phase 1
Development phase
19 participants
Enrollment target

Study Summary

The use of lidocaine, as an anesthetic drug, during implantation of an implantable cardioverter-defibrillator(ICD)will not result in a clinically significant alteration of the defibrillation threshold during ICD placement.

Primary Outcome

These patients will receive a standard dose of intravenous lidocaine (for attenuation of pain associated with propofol injection) versus patients who do not receive an intravenous lidocaine dose. Outcome is to have a success defibrillation within the first attempt.

Interventions

  • DRUG Placebo
  • DRUG lidocaine

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2010-01
Est. Completion 2010-05
Phase Phase 1

Why NCT03117166 stopped before completion

NCT03117166 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT03117166 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03117166 about?

NCT03117166 is a clinical study titled "Effect of Intravenous Lidocaine, Used to Attenuate Pain With Propofol Injection, on Defibrillation Threshold Testing". The use of lidocaine, as an anesthetic drug, during implantation of an implantable cardioverter-defibrillator(ICD)will not result in a clinically significant alteration of the defibrillation threshold during ICD placement.

What is the current status of trial NCT03117166?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2010-01. Estimated completion is 2010-05.

What interventions are being tested in trial NCT03117166?

The interventions under investigation include: Placebo (DRUG), lidocaine (DRUG).

Who is sponsoring clinical trial NCT03117166?

This trial is sponsored by Drexel University College of Medicine, which has 25 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03117166's enrollment target sits among peer trials

19 1716th of 2000 higher than 281 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03117166, the US trial registry maintained by the National Library of Medicine. NCT03117166 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.