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NCT03115801 · ClinicalTrials.gov registry record · Phase 2

A Phase II Randomized Trial of Immunotherapy Plus Radiotherapy in Metastatic Genitourinary Cancers

A Phase 2 study, sponsored by Weill Medical College of Cornell University.

Terminated
Registry status
Phase 2
Development phase
6
Enrollment target

NCT03115801: Clinical Trial Phase 2 study, sponsored by Weill Medical College of Cornell University.

NCT03115801 is a Phase 2 study that was terminated before completion, run by Weill Medical College of Cornell University. The registered enrollment target is 6 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03115801, a Phase 2 study, was terminated before completion, sponsored by Weill Medical College of Cornell University.

TERMINATED
Registry status
Phase 2
Development phase
6 participants
Enrollment target

Study Summary

The trial is open to patients who have metastatic renal cell carcinoma/urothelial (bladder) carcinoma with at least 2 measurable sites of disease. All eligible patients will be randomly assigned to immunotherapy(nivolumab/atezolizumab/pembrolizumab) versus immunotherapy (nivolumab/atezolizumab/pembrolizumab) plus radiotherapy, 10 Gy x3 (conformally or by intensity modulation radiation therapy/Image-guided radiation therapy (IMRT/IGRT) to maximally spare normal tissue), to one of their measurable lesions.

Interventions

  • DRUG Pembrolizumab
  • DRUG Atezolizumab
  • DRUG Nivolumab
  • RADIATION Radiation & immunotherapy

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2016-11
Est. Completion 2020-10-13
Phase Phase 2

Why NCT03115801 stopped before completion

NCT03115801 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 4 interventions - of which Pembrolizumab is the first listed.

NCT03115801 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03115801 about?

NCT03115801 is a clinical study titled "A Phase II Randomized Trial of Immunotherapy Plus Radiotherapy in Metastatic Genitourinary Cancers". The trial is open to patients who have metastatic renal cell carcinoma/urothelial (bladder) carcinoma with at least 2 measurable sites of disease. All eligible patients will be randomly assigned to immunotherapy(nivolumab/atezolizumab/pembrolizumab) versus immunotherapy (nivolumab/atezolizumab/pembr...

What is the current status of trial NCT03115801?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 2016-11. Estimated completion is 2020-10-13.

What interventions are being tested in trial NCT03115801?

The interventions under investigation include: Pembrolizumab (DRUG), Atezolizumab (DRUG), Nivolumab (DRUG), Radiation & immunotherapy (RADIATION).

Who is sponsoring clinical trial NCT03115801?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03115801's enrollment target sits among peer trials

6 1996th of 2000 higher than 1 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03115801, the US trial registry maintained by the National Library of Medicine. NCT03115801 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.