Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03089866 · ClinicalTrials.gov registry record
Effect of Sedation on Cognitive Performance in the Elderly
A clinical trial, sponsored by University of Alabama at Birmingham.
- Completed
- Registry status
- 20
- Enrollment target
NCT03089866: Completed study, sponsored by University of Alabama at Birmingham.
NCT03089866 is a clinical trial that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 20 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03089866 has completed, sponsored by University of Alabama at Birmingham.
- COMPLETED
- Registry status
- 20 participants
- Enrollment target
Study Summary
The main goal of this study is to allow the anesthesiologist to make a more informed decision about the anesthetic requirement of a person prior to starting anesthesia. The preliminary data collected in this study will support a larger investigation aimed at gaining a better understanding of anesthetic susceptibility in general and in the elderly population which appears to be at greater risk for Postoperative Cognitive Dysfunction (POCD) POCD is a short-term decline in cognitive function (especially in memory and executive functions) that may last from a few days to a few weeks after surgery. In rare cases, this disorder may persist for several months after major surgery. POCD is distinct from emergence delirium. It occurs most commonly in older patients and those with pre-existing cognitive impairment. POCD is common in adult patients of all ages at hospital discharge after major non-cardiac surgery, but only the elderly (aged 60 years or older) are at significant risk for long-term cognitive problems. The body's inflammatory response to surgery likely plays an important role, at least in elderly patients. Investigators also postulate that a relative 'anesthetic overdose' may be a significant risk factor. Hence, being able to make a better judgment on the dose needed for an individual is extremely important.
Primary Outcome
Change in Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) scores before and after sedation
Interventions
- DRUG Midazolam (0.02mg/kg)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2015-03 |
| Est. Completion | 2020-09-04 |
What the finished NCT03089866 record still lists
NCT03089866 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Midazolam (0.02mg/kg) is the first listed.
NCT03089866 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03089866 about?
NCT03089866 is a clinical study titled "Effect of Sedation on Cognitive Performance in the Elderly". The main goal of this study is to allow the anesthesiologist to make a more informed decision about the anesthetic requirement of a person prior to starting anesthesia. The preliminary data collected in this study will support a larger investigation aimed at gaining a better understanding of anesthe...
What is the current status of trial NCT03089866?
This trial is currently completed. The enrollment target is 20 participants. The study started on 2015-03. Estimated completion is 2020-09-04.
What interventions are being tested in trial NCT03089866?
The interventions under investigation include: Midazolam (0.02mg/kg) (DRUG).
Who is sponsoring clinical trial NCT03089866?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00573339 · 20 participants
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing
- NCT00692939 · 20 participants · Phase 1
Autologous Stem Cell Transplantation for Crohn's Disease
- NCT00967785 · 20 participants · Phase 1
A Phase I Study of Mozobil in the Treatment of Patients With WHIMS
- NCT01406691 · 20 participants · Phase 4
Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia